Working Group Webinar Library
Webinar Library
A Gene Regulatory Switch Promotes a New Therapeutic Vulnerability in EGFR Inhibitor Drug Tolerant Persister Cells
This presentation is an introduction to Oncology Data Science at AstraZeneca and the important work being done to impact decision making to advance AstraZeneca’s oncology drug portfolio. Steven Criscione will also share a research vignette on our study of the EGFR inhibitor osimertinib drug tolerant persister cells.

Transforming Complex Information Into Compelling, Human Stories
Learn strategies for translating even the most technical information into compelling, human stories—so you can change the way people think, feel, and act. We’ll use sustainability communications as our lens for looking at messaging strategies that work (and those that don’t work). We’ll also talk about the buzzwords and cliches you should avoid in your writing. Finally, we’ll practice what we’ve learned with a simple writing exercise that brings the concepts to life. This session requires audience participation, so bring your ideas, your questions, and something to write with. Watch the Recording Presenter

Prevails and Mirages of Large Language Models in Clinical NLP
This talk will introduce the technologies powering LLMs, overview the recent prevails, and examine the mirages in the hype of LLM magic. Based on the experience in developing two clinical LLMs in the clinical domain, including GatorTron and GatorTronGPT, this talk will provide insight into the potential application of LLMs for clinical NLP and healthcare.

Reducing Diagnostic Delays in Acute Hepatic Porphyria Using Health Records Data and Machine Learning
Acute hepatic porphyria (AHP) is a rare but treatable condition with an average diagnostic delay of 15 years. Utilizing electronic health records (EHR) data and machine learning (ML) can potentially improve the timely recognition of AHP. This study used structured and notes-based EHR data from UCSF and UCLA to develop models predicting who will be referred for AHP testing and who will test positive. The referral model achieved an F-score of 86%-91%, and the diagnosis model achieved an F-score of 92%.

Translational Artificial Intelligence in Advancing Learning Health System (LHS) Systems
Learning health system (LHS) aims to leverage technology, data analytics, and evidence-based practices to create a feedback loop that continuously informs healthcare delivery, policy, and practice. It requires a multidisciplinary approach to interpret patterns observed in real-world data with the associated context.
