Precision medicine informatics.
Author(s): Frey, Lewis J, Bernstam, Elmer V, Denny, Joshua C
DOI: 10.1093/jamia/ocw053
Author(s): Frey, Lewis J, Bernstam, Elmer V, Denny, Joshua C
DOI: 10.1093/jamia/ocw053
Standards requiring education in informatics in pharmacy curricula were introduced in the last 10 years by the Accreditation Council for Pharmacy Education. Mirroring difficulties faced by other health professions educators, implementation of these requirements remains fragmented and somewhat limited across colleges of pharmacy in the US. Clinical practice and workforce metrics underline a pronounced need for clinicians with varying competencies in health informatics. In response to these challenges, a multitiered [...]
Author(s): Breeden, Elizabeth A, Clauson, Kevin A
DOI: 10.1093/jamia/ocw023
Cancer has been extensively characterized on the basis of genomics. The integration of genetic information about cancers with data on how the cancers respond to target based therapy to help to optimum cancer treatment.
Author(s): Cheng, Lijun, Schneider, Bryan P, Li, Lang
DOI: 10.1093/jamia/ocw004
Since the launch of the clinical informatics subspecialty for physicians in 2013, over 1100 physicians have used the practice and education pathways to become board-certified in clinical informatics. Starting in 2018, only physicians who have completed a 2-year clinical informatics fellowship program accredited by the Accreditation Council on Graduate Medical Education will be eligible to take the board exam. The purpose of this viewpoint piece is to describe the collective [...]
Author(s): Longhurst, Christopher A, Pageler, Natalie M, Palma, Jonathan P, Finnell, John T, Levy, Bruce P, Yackel, Thomas R, Mohan, Vishnu, Hersh, William R
DOI: 10.1093/jamia/ocv209
To understand how consumer questions on online resources differ from questions asked by professionals, and how such consumer questions differ across resources.
Author(s): Roberts, Kirk, Demner-Fushman, Dina
DOI: 10.1093/jamia/ocw024
Identifying disease-mutation relationships is a significant challenge in the advancement of precision medicine. The aim of this work is to design a tool that automates the extraction of disease-related mutations from biomedical text to advance database curation for the support of precision medicine.
Author(s): Singhal, Ayush, Simmons, Michael, Lu, Zhiyong
DOI: 10.1093/jamia/ocw041
(1) To develop an automated algorithm to predict a patient's response (ie, if the patient agrees or declines) before he/she is approached for a clinical trial invitation; (2) to assess the algorithm performance and the predictors on real-world patient recruitment data for a diverse set of clinical trials in a pediatric emergency department; and (3) to identify directions for future studies in predicting patients' participation response.
Author(s): Ni, Yizhao, Beck, Andrew F, Taylor, Regina, Dyas, Jenna, Solti, Imre, Grupp-Phelan, Jacqueline, Dexheimer, Judith W
DOI: 10.1093/jamia/ocv216
This article offers suggested guidelines for graduate students who are embarking on informatics doctoral studies and anticipating the dissertation research and its documentation. Much of the guidance is pertinent for writing dissertations in other disciplines as well. The messages are largely directed at doctoral students, but some elements are also pertinent for master's students. All are relevant for faculty research advisors. The value of the dissertation is often underestimated. Too [...]
Author(s): Shortliffe, Edward H
DOI: 10.1093/jamia/ocw074
Informatics programs need assurance that their curricula prepare students for intended roles as well as ensuring that students have mastered the appropriate competencies. The objective of this study is to describe a method for using assessment data to identify areas for curriculum, student selection, and assessment improvement.
Author(s): Berner, Eta S, Dorsey, Amanda D, Garrie, Robert L, Qu, Haiyan
DOI: 10.1093/jamia/ocw073
To move beyond a select few genes/drugs, the successful adoption of pharmacogenomics into routine clinical care requires a curated and machine-readable database of pharmacogenomic knowledge suitable for use in an electronic health record (EHR) with clinical decision support (CDS). Recognizing that EHR vendors do not yet provide a standard set of CDS functions for pharmacogenetics, the Clinical Pharmacogenetics Implementation Consortium (CPIC) Informatics Working Group is developing and systematically incorporating a [...]
Author(s): Hoffman, James M, Dunnenberger, Henry M, Kevin Hicks, J, Caudle, Kelly E, Whirl Carrillo, Michelle, Freimuth, Robert R, Williams, Marc S, Klein, Teri E, Peterson, Josh F
DOI: 10.1093/jamia/ocw027