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This paper describes our considerations and methods for implementing an open-source centralized research data repository (CRDR) and reports its impact on retrospective outcomes research capacity in the urology department at Columbia University. We performed retrospective pretest and post-test analyses of user acceptance, workflow efficiency, and publication quantity and quality (measured by journal impact factor) before and after the implementation. The CRDR transformed the research workflow and enabled a new research [...]

The clinical element model (CEM) is an information model designed for representing clinical information in electronic health records (EHR) systems across organizations. The current representation of CEMs does not support formal semantic definitions and therefore it is not possible to perform reasoning and consistency checking on derived models. This paper introduces our efforts to represent the CEM specification using the Web Ontology Language (OWL). The CEM-OWL representation connects the CEM [...]

To adapt and automate the medication regimen complexity index (MRCI) within the structure of a commercial medication database in the post-acute home care setting.

Patient portal use has been associated with favorable outcomes, but we know less about how patients use and benefit from specific patient portal features.

Privacy-preserving data publishing addresses the problem of disclosing sensitive data when mining for useful information. Among existing privacy models, ε-differential privacy provides one of the strongest privacy guarantees and makes no assumptions about an adversary's background knowledge. All existing solutions that ensure ε-differential privacy handle the problem of disclosing relational and set-valued data in a privacy-preserving manner separately. In this paper, we propose an algorithm that considers both relational and [...]

To explore the applicability of a syndromic surveillance method to the early detection of health information technology (HIT) system failures.

To evaluate an online disease management system supporting patients with uncontrolled type 2 diabetes.

Medication  safety requires that each drug be monitored throughout its market life as early detection of adverse drug reactions (ADRs) can lead to alerts that prevent patient harm. Recently, electronic medical records (EMRs) have emerged as a valuable resource for pharmacovigilance. This study examines the use of retrospective medication orders and inpatient laboratory results documented in the EMR to identify ADRs.

This paper summarizes much of the research that is applicable to the design of auditory alarms in a medical context. It also summarizes research that demonstrates that false alarm rates are unacceptably high, meaning that the proper application of auditory alarm design principles are compromised.