Modeling temporal relationships in large scale clinical associations.
We describe an approach for modeling temporal relationships in a large scale association analysis of electronic health record data. The addition of temporal information can inform hypothesis generation and help to explain the relationships. We applied this approach on a dataset containing 41.2 million time-stamped International Classification of Diseases, Ninth Revision (ICD-9) codes from 1.6 million patients.
Author(s): Hanauer, David A, Ramakrishnan, Naren
DOI: 10.1136/amiajnl-2012-001117