Developing knowledge resources to support precision medicine: principles from the Clinical Pharmacogenetics Implementation Consortium (CPIC).
To move beyond a select few genes/drugs, the successful adoption of pharmacogenomics into routine clinical care requires a curated and machine-readable database of pharmacogenomic knowledge suitable for use in an electronic health record (EHR) with clinical decision support (CDS). Recognizing that EHR vendors do not yet provide a standard set of CDS functions for pharmacogenetics, the Clinical Pharmacogenetics Implementation Consortium (CPIC) Informatics Working Group is developing and systematically incorporating a [...]
Author(s): Hoffman, James M, Dunnenberger, Henry M, Kevin Hicks, J, Caudle, Kelly E, Whirl Carrillo, Michelle, Freimuth, Robert R, Williams, Marc S, Klein, Teri E, Peterson, Josh F
DOI: 10.1093/jamia/ocw027