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Studies that use patient smartphones to collect ecological momentary assessment and sensor data, an approach frequently referred to as digital phenotyping, have increased in popularity in recent years. There is a lack of formal guidelines for the design of new digital phenotyping studies so that they are powered to detect both population-level longitudinal associations as well as individual-level change points in multivariate time series. In particular, determining the appropriate balance [...]

Accurate estimations of surgical case durations can lead to the cost-effective utilization of operating rooms. We developed a novel machine learning approach, using both structured and unstructured features as input, to predict a continuous probability distribution of surgical case durations.

Disease surveillance systems are expanding using electronic health records (EHRs). However, there are many challenges in this regard. In the present study, the solutions and challenges of implementing EHR-based disease surveillance systems (EHR-DS) have been reviewed.

The goal of this study is to explore transformer-based models (eg, Bidirectional Encoder Representations from Transformers [BERT]) for clinical concept extraction and develop an open-source package with pretrained clinical models to facilitate concept extraction and other downstream natural language processing (NLP) tasks in the medical domain.

A growing body of observational data enabled its secondary use to facilitate clinical care for complex cases not covered by the existing evidence. We conducted a scoping review to characterize clinical decision support systems (CDSSs) that generate new knowledge to provide guidance for such cases in real time.

To assess usability and usefulness of a machine learning-based order recommender system applied to simulated clinical cases.

In a biomedical literature search, the link between a query and a document is often not established, because they use different terms to refer to the same concept. Distributional word embeddings are frequently used for detecting related words by computing the cosine similarity between them. However, previous research has not established either the best embedding methods for detecting synonyms among related word pairs or how effective such methods may be.

The development of machine learning (ML) algorithms to address a variety of issues faced in clinical practice has increased rapidly. However, questions have arisen regarding biases in their development that can affect their applicability in specific populations. We sought to evaluate whether studies developing ML models from electronic health record (EHR) data report sufficient demographic data on the study populations to demonstrate representativeness and reproducibility.

This case report describes the innovative design and build of an algorithm that integrates available data from separate hospital-based informatics systems, which perform different daily functions to augment the contact-tracing process of COVID-19 patients by identifying exposed neighboring patients and healthcare workers and assessing their risk. Prior to the establishment of the algorithm, contact-tracing teams comprising 6 members would spend up to 10 hours each to complete contact tracing for [...]