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Substance use disorder (SUD) care continues to be hindered by persistent gaps in health information exchange (HIE). This study examined people, organizational, regulatory, and technical barriers to SUD data sharing from the provider perspective and identified key opportunities to improve care through health record interoperability.

To evaluate the comparative effectiveness of ambient documentation tools (ADTs) with distinct architectures (Tablet-Based Virtual Human-Assisted Ambient [Tool A], EHR-Integrated Ambient [Tool B], and Standalone Ambient [Tool C]) on provider efficiency, documentation burden, and productivity in primary care.

Machine learning (ML) models are increasingly being developed to support healthcare delivery. However, concerns remain about their potential to perpetuate existing biases rooted in the data used to develop them. We aim to assess the impact of using race in predicting hospital admission probabilities for patients visiting the emergency department (ED).

Disease profiles and access to care differ between rural and urban populations. The aim of this study is to examine the association of rurality with electronic health record-derived disease profiles and heart failure risk.

Childhood obesity and respiratory tract infections (RTIs) are 2 major global public health issues that frequently co-occur and are closely interrelated. Early detection of children with prior RTIs who are at high obesity risk is crucial for targeted interventions. This study integrates interpretable machine learning (ML) models and a deep learning network to develop an obesity risk prediction model in a large pediatric cohort.

Clinicians are increasingly using emoji in digital communication, but limited qualitative work has examined how they assess the appropriateness, risks, and benefits of this practice.

Embedded pragmatic clinical trials (ePCTs) are conducted as part of routine clinical care and therefore use data collected from real-world data sources, such as electronic health record systems and administrative claims. A common approach for using these types of data across all phases of trial conduct is to create a computable phenotype (an explicitly defined data query data, including specified data types, data codes, and logical parameters) to capture patients [...]

To develop a machine learning (ML) model to predict magnetic resonance imaging (MRI) appointment no-shows and test the effectiveness of a targeted phone call intervention in reducing the no-show rate.

To clarify how validation requirements should be specified for medical digital twins used in clinical decision support, particularly when such systems are intended to compare interventions, treatment timings, dosages, or sequential care strategies.

To evaluate the real-world performance of a transformer-based natural language processing (NLP) system for extracting Social Determinants of Health (SDoH) from clinical notes, using survey-based SDoH measures a reference comparators.