OpenSep: a generalizable open source pipeline for SOFA score calculation and Sepsis-3 classification.
EHR-based sepsis research often uses heterogeneous definitions of sepsis leading to poor generalizability and difficulty in comparing studies to each other. We have developed OpenSep, an open-source pipeline for sepsis phenotyping according to the Sepsis-3 definition, as well as determination of time of sepsis onset and SOFA scores. The Minimal Sepsis Data Model was developed alongside the pipeline to enable the execution of the pipeline to diverse sources of electronic [...]
Author(s): Hofford, Mackenzie R, Yu, Sean C, Johnson, Alistair E W, Lai, Albert M, Payne, Philip R O, Michelson, Andrew P
DOI: 10.1093/jamiaopen/ooac105