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With extended life expectancy, the number of people in need of care has been growing. To optimally support them, it is important to know the patterns and conditions of their daily life that influence the need for support, and thus, the classification of the care need. In this study, we aim to utilize a large corpus consisting of care benefits applications to do an explorative analysis of factors affecting care [...]

To compare clinical summaries generated from simulated patient primary care electronic health records (EHRs) by GPT-4, to summaries generated by clinicians on multiple domains of quality including utility, concision, accuracy, and bias.

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that disproportionately affects women and racial/ethnic minority groups. Predicting disease flares is essential for improving patient outcomes, yet few studies integrate both clinical and social determinants of health (SDoH). We therefore developed FLAME (FLAre Machine learning prediction of SLE), a machine learning pipeline that uses electronic health records (EHRs) and contextual-level SDoH to predict 3-month flare risk, emphasizing explainability and fairness.

Recent advancements of Artificial Intelligence (AI) are rapidly transforming clinical research. While this technology offers exciting opportunities, it amplifies existing concerns regarding the need for transparent methodology that fosters patient engagement, and introduces new challenges. PCORI's Improving Methods portfolio has invested in methodological research to enhance rigor and transparency via patient-centered approaches in AI.

School violence risk prevention in the United States relies on manual assessments that are time-consuming and subjective. We developed a machine learning algorithm named Automated RIsk Assessment (ARIA), using natural language processing (NLP) to find linguistic patterns in standardized interview questions that can predict risk of aggression. Our goal was to evaluate the incremental change in performance with the addition of each question to simulate situations where interviews cannot be [...]

Our objective was to determine how social vulnerabilities, broadband access, and rurality relate to telemedicine use across the United States through large-scale analysis of real-world telemedicine data.

To improve the identification of patients with health-related social needs (HRSNs) in the emergency department (ED), we developed and integrated a risk prediction score into an existing Fast Healthcare Interoperability Resources (FHIR)-based clinical decision support (CDS).

To assess the effect of a digital scribe among pediatric providers on documentation time, cognitive load, burnout, and caregiver satisfaction.

To assess the calibration of 9 large language models (LLMs) within biomedical natural language processing (BioNLP) tasks, furthering understanding of trustworthiness and reliability in real-world settings.

We aim to leverage more comprehensive phenotypic and genotypic clinical data to enhance the treatment response predictions.