Addressing methodological and logistical challenges of using electronic health record (EHR) data for research.
Author(s): Bakken, Suzanne
DOI: 10.1093/jamia/ocae126
Author(s): Bakken, Suzanne
DOI: 10.1093/jamia/ocae126
Medical research faces substantial challenges from noisy labels attributed to factors like inter-expert variability and machine-extracted labels. Despite this, the adoption of label noise management remains limited, and label noise is largely ignored. To this end, there is a critical need to conduct a scoping review focusing on the problem space. This scoping review aims to comprehensively review label noise management in deep learning-based medical prediction problems, which includes label [...]
Author(s): Wei, Yishu, Deng, Yu, Sun, Cong, Lin, Mingquan, Jiang, Hongmei, Peng, Yifan
DOI: 10.1093/jamia/ocae108
Predicting mortality after acute myocardial infarction (AMI) is crucial for timely prescription and treatment of AMI patients, but there are no appropriate AI systems for clinicians. Our primary goal is to develop a reliable and interpretable AI system and provide some valuable insights regarding short, and long-term mortality.
Author(s): Kim, Minwook, Kang, Donggil, Kim, Min Sun, Choe, Jeong Cheon, Lee, Sun-Hack, Ahn, Jin Hee, Oh, Jun-Hyok, Choi, Jung Hyun, Lee, Han Cheol, Cha, Kwang Soo, Jang, Kyungtae, Bong, WooR I, Song, Giltae, Lee, Hyewon
DOI: 10.1093/jamia/ocae114
We sought to (1) characterize the process of diagnosing pneumonia in an emergency department (ED) and (2) examine clinician reactions to a clinician-facing diagnostic discordance feedback tool.
Author(s): Butler, Jorie M, Taft, Teresa, Taber, Peter, Rutter, Elizabeth, Fix, Megan, Baker, Alden, Weir, Charlene, Nevers, McKenna, Classen, David, Cosby, Karen, Jones, Makoto, Chapman, Alec, Jones, Barbara E
DOI: 10.1093/jamia/ocae112
In acute chest pain management, risk stratification tools, including medical history, are recommended. We compared the fraction of patients with sufficient clinical data obtained using computerized history taking software (CHT) versus physician-acquired medical history to calculate established risk scores and assessed the patient-by-patient agreement between these 2 ways of obtaining medical history information.
Author(s): Brandberg, Helge, Sundberg, Carl Johan, Spaak, Jonas, Koch, Sabine, Kahan, Thomas
DOI: 10.1093/jamia/ocae110
Healthcare providers employ heuristic and analytical decision-making to navigate the high-stakes environment of the emergency department (ED). Despite the increasing integration of information systems (ISs), research on their efficacy is conflicting. Drawing on related fields, we investigate how timing and mode of delivery influence IS effectiveness. Our objective is to reconcile previous contradictory findings, shedding light on optimal IS design in the ED.
Author(s): Born, Cornelius, Schwarz, Romy, Böttcher, Timo Phillip, Hein, Andreas, Krcmar, Helmut
DOI: 10.1093/jamia/ocae096
Healthcare organizations, including Clinical and Translational Science Awards (CTSA) hubs funded by the National Institutes of Health, seek to enable secondary use of electronic health record (EHR) data through an enterprise data warehouse for research (EDW4R), but optimal approaches are unknown. In this qualitative study, our goal was to understand EDW4R impact, sustainability, demand management, and accessibility.
Author(s): Campion, Thomas R, Craven, Catherine K, Dorr, David A, Bernstam, Elmer V, Knosp, Boyd M
DOI: 10.1093/jamia/ocae111
Surface the urgent dilemma that healthcare delivery organizations (HDOs) face navigating the US Food and Drug Administration (FDA) final guidance on the use of clinical decision support (CDS) software.
Author(s): Sendak, Mark P, Liu, Vincent X, Beecy, Ashley, Vidal, David E, Shaw, Keo, Lifson, Mark A, Tobey, Danny, Valladares, Alexandra, Loufek, Brenna, Mogri, Murtaza, Balu, Suresh
DOI: 10.1093/jamia/ocae119
This study evaluates regularization variants in logistic regression (L1, L2, ElasticNet, Adaptive L1, Adaptive ElasticNet, Broken adaptive ridge [BAR], and Iterative hard thresholding [IHT]) for discrimination and calibration performance, focusing on both internal and external validation.
Author(s): Fridgeirsson, Egill A, Williams, Ross, Rijnbeek, Peter, Suchard, Marc A, Reps, Jenna M
DOI: 10.1093/jamia/ocae109
Synthesizing and evaluating inconsistent medical evidence is essential in evidence-based medicine. This study aimed to employ ChatGPT as a sophisticated scientific reasoning engine to identify conflicting clinical evidence and summarize unresolved questions to inform further research.
Author(s): Xie, Shiyao, Zhao, Wenjing, Deng, Guanghui, He, Guohua, He, Na, Lu, Zhenhua, Hu, Weihua, Zhao, Mingming, Du, Jian
DOI: 10.1093/jamia/ocae100