Making it personal: translational bioinformatics.
Author(s): Butte, Atul J, Ohno-Machado, Lucila
DOI: 10.1136/amiajnl-2013-002028
Author(s): Butte, Atul J, Ohno-Machado, Lucila
DOI: 10.1136/amiajnl-2013-002028
To compare the manifestations, mechanisms, and rates of system-related errors associated with two electronic prescribing systems (e-PS). To determine if the rate of system-related prescribing errors is greater than the rate of errors prevented.
Author(s): Westbrook, Johanna I, Baysari, Melissa T, Li, Ling, Burke, Rosemary, Richardson, Katrina L, Day, Richard O
DOI: 10.1136/amiajnl-2013-001745
Patient portals are becoming increasingly common, but the safety of patient messages and eVisits has not been well studied. Unlike patient-to-nurse telephonic communication, patient messages and eVisits involve an asynchronous process that could be hazardous if patients were using it for time-sensitive symptoms such as chest pain or dyspnea.
Author(s): North, Frederick, Crane, Sarah J, Stroebel, Robert J, Cha, Stephen S, Edell, Eric S, Tulledge-Scheitel, Sidna M
DOI: 10.1136/amiajnl-2012-001208
To provide an overview of the problem of temporal reasoning over clinical text and to summarize the state of the art in clinical natural language processing for this task.
Author(s): Sun, Weiyi, Rumshisky, Anna, Uzuner, Ozlem
DOI: 10.1136/amiajnl-2013-001760
As people increasingly engage in online health-seeking behavior and contribute to health-oriented websites, the volume of medical text authored by patients and other medical novices grows rapidly. However, we lack an effective method for automatically identifying medical terms in patient-authored text (PAT). We demonstrate that crowdsourcing PAT medical term identification tasks to non-experts is a viable method for creating large, accurately-labeled PAT datasets; moreover, such datasets can be used to [...]
Author(s): MacLean, Diana Lynn, Heer, Jeffrey
DOI: 10.1136/amiajnl-2012-001110
To employ machine learning methods to predict the eventual therapeutic response of breast cancer patients after a single cycle of neoadjuvant chemotherapy (NAC).
Author(s): Mani, Subramani, Chen, Yukun, Li, Xia, Arlinghaus, Lori, Chakravarthy, A Bapsi, Abramson, Vandana, Bhave, Sandeep R, Levy, Mia A, Xu, Hua, Yankeelov, Thomas E
DOI: 10.1136/amiajnl-2012-001332
Health social networking sites (HSNS), virtual communities where users connect with each other around common problems and share relevant health data, have been increasingly adopted by medical professionals and patients. The growing use of HSNS like Sermo and PatientsLikeMe has prompted public concerns about the risks that such online data-sharing platforms pose to the privacy and security of personal health data. This paper articulates a set of privacy risks introduced [...]
Author(s): Li, Jingquan
DOI: 10.1136/amiajnl-2012-001500
DNA methylation, a regulator of gene expression, plays an important role in diverse biological processes including developmental process, carcinogenesis and aging. In particular, aberrant DNA methylation has been largely observed in several types of cancers. Currently, it is important to extract disease-specific gene sets associated with the regulation of DNA methylation.
Author(s): Joung, Je-Gun, Kim, Dokyoon, Kim, Kyung Hwa, Kim, Ju Han
DOI: 10.1136/amiajnl-2012-001571
To develop a comprehensive temporal information extraction system that can identify events, temporal expressions, and their temporal relations in clinical text. This project was part of the 2012 i2b2 clinical natural language processing (NLP) challenge on temporal information extraction.
Author(s): Tang, Buzhou, Wu, Yonghui, Jiang, Min, Chen, Yukun, Denny, Joshua C, Xu, Hua
DOI: 10.1136/amiajnl-2013-001635
The Sixth Informatics for Integrating Biology and the Bedside (i2b2) Natural Language Processing Challenge for Clinical Records focused on the temporal relations in clinical narratives. The organizers provided the research community with a corpus of discharge summaries annotated with temporal information, to be used for the development and evaluation of temporal reasoning systems. 18 teams from around the world participated in the challenge. During the workshop, participating teams presented comprehensive [...]
Author(s): Sun, Weiyi, Rumshisky, Anna, Uzuner, Ozlem
DOI: 10.1136/amiajnl-2013-001628