Explicit causal reasoning is needed to prevent prognostic models being victims of their own success.
Author(s): Sperrin, Matthew, Jenkins, David, Martin, Glen P, Peek, Niels
DOI: 10.1093/jamia/ocz197
Author(s): Sperrin, Matthew, Jenkins, David, Martin, Glen P, Peek, Niels
DOI: 10.1093/jamia/ocz197
The Phenotype Risk Score (PheRS) is a method to detect Mendelian disease patterns using phenotypes from the electronic health record (EHR). We compared the performance of different approaches mapping EHR phenotypes to Mendelian disease features.
Author(s): Bastarache, Lisa, Hughey, Jacob J, Goldstein, Jeffrey A, Bastraache, Julie A, Das, Satya, Zaki, Neil Charles, Zeng, Chenjie, Tang, Leigh Anne, Roden, Dan M, Denny, Joshua C
DOI: 10.1093/jamia/ocz179
Emergency departments (EDs) continue to pursue optimal patient flow without sacrificing quality of care. The speed with which a healthcare provider receives pertinent information, such as results from clinical orders, can impact flow. We seek to determine if clinical ordering behavior can be predicted at triage during an ED visit.
Author(s): Hunter-Zinck, Haley S, Peck, Jordan S, Strout, Tania D, Gaehde, Stephan A
DOI: 10.1093/jamia/ocz171
Artificial pancreas systems aim to reduce the burden of type 1 diabetes by automating insulin dosing. These systems link a continuous glucose monitor (CGM) and insulin pump with a control algorithm, but require users to announce meals, without which the system can only react to the rise in blood glucose.
Author(s): Zheng, Min, Ni, Baohua, Kleinberg, Samantha
DOI: 10.1093/jamia/ocz159
Electronic health records (EHR) data have become a central data source for clinical research. One concern for using EHR data is that the process through which individuals engage with the health system, and find themselves within EHR data, can be informative. We have termed this process informed presence. In this study we use simulation and real data to assess how the informed presence can impact inference.
Author(s): Goldstein, Benjamin A, Phelan, Matthew, Pagidipati, Neha J, Peskoe, Sarah B
DOI: 10.1093/jamia/ocz148
Population-level prevention activities are often publicly invisible and excluded in planning and policymaking. This creates an incomplete picture of prevention service-related inputs, particularly at the local level. We describe the process and lessons learned by the Public Health Activities and Services Tracking team in promoting adoption of standardized service delivery measures developed to assess public health inputs and guide system transformations. The 3 factors depicted in our Public Health Activities [...]
Author(s): Bekemeier, Betty, Park, Seungeun, Whitman, Greg
DOI: 10.1093/jamia/ocz160
Extracting clinical entities and their attributes is a fundamental task of natural language processing (NLP) in the medical domain. This task is typically recognized as 2 sequential subtasks in a pipeline, clinical entity or attribute recognition followed by entity-attribute relation extraction. One problem of pipeline methods is that errors from entity recognition are unavoidably passed to relation extraction. We propose a novel joint deep learning method to recognize clinical entities [...]
Author(s): Shi, Xue, Yi, Yingping, Xiong, Ying, Tang, Buzhou, Chen, Qingcai, Wang, Xiaolong, Ji, Zongcheng, Zhang, Yaoyun, Xu, Hua
DOI: 10.1093/jamia/ocz158
We describe the use of an online patient portal to recruit and enroll primary care patients in a randomized trial testing the effectiveness of a colorectal cancer (CRC) screening decision support program. We use multiple logistic regression to identify patient characteristics associated with trial recruitment, enrollment, and engagement. We found that compared to Whites, Blacks had lower odds of viewing the portal message (OR = 0.46, 95% CI = 0.37-0.57), opening the attached link [...]
Author(s): Tabriz, Amir Alishahi, Fleming, Patrice Jordan, Shin, Yongyun, Resnicow, Ken, Jones, Resa M, Flocke, Susan A, Shires, Deirdre A, Hawley, Sarah T, Willens, David, Lafata, Jennifer Elston
DOI: 10.1093/jamia/ocz157
Effective diabetes problem solving requires identification of risk factors for inadequate mealtime self-management. Ecological momentary assessment was used to enhance identification of factors hypothesized to impact self-management. Adolescents with type 1 diabetes participated in a feasibility trial for a mobile app called MyDay. Meals, mealtime insulin, self-monitored blood glucose, and psychosocial and contextual data were obtained for 30 days. Using 1472 assessments, mixed-effects between-subjects analyses showed that social context, location [...]
Author(s): Mulvaney, Shelagh A, Vaala, Sarah E, Carroll, Rachel B, Williams, Laura K, Lybarger, Cindy K, Schmidt, Douglas C, Dietrich, Mary S, Laffel, Lori M, Hood, Korey K
DOI: 10.1093/jamia/ocz147
To investigate the effects of adjusting the default order set settings on telemetry usage.
Author(s): Rubins, David, Boxer, Robert, Landman, Adam, Wright, Adam
DOI: 10.1093/jamia/ocz137