Advancing the application and evaluation of large language models in health and biomedicine.
Author(s): Bakken, Suzanne
DOI: 10.1093/jamia/ocaf043
Author(s): Bakken, Suzanne
DOI: 10.1093/jamia/ocaf043
[This corrects the article DOI: 10.1093/jamiaopen/ooaf007.].
Author(s):
DOI: 10.1093/jamiaopen/ooaf028
The Safety Assurance Factors for Electronic Health Record (EHR) Resilience (SAFER) Guides provide recommendations to healthcare organizations for conducting proactive self-assessments of the safety and effectiveness of their EHR implementation and use. Originally released in 2014, they were last updated in 2016. In 2022, the Centers for Medicare and Medicaid Services required their annual attestation by US hospitals.
Author(s): Sittig, Dean F, Flanagan, Trisha, Sengstack, Patricia, Cholankeril, Rosann T, Ehsan, Sara, Heidemann, Amanda, Murphy, Daniel R, Salmasian, Hojjat, Adelman, Jason S, Singh, Hardeep
DOI: 10.1093/jamia/ocaf018
Recent advances in deep learning show significant potential in analyzing continuous monitoring electronic health records (EHR) data for clinical outcome prediction. We aim to develop a Transformer-based, Encounter-level Clinical Outcome (TECO) model to predict mortality in the intensive care unit (ICU) using inpatient EHR data.
Author(s): Rong, Ruichen, Gu, Zifan, Lai, Hongyin, Nelson, Tanna L, Keller, Tony, Walker, Clark, Jin, Kevin W, Chen, Catherine, Navar, Ann Marie, Velasco, Ferdinand, Peterson, Eric D, Xiao, Guanghua, Yang, Donghan M, Xie, Yang
DOI: 10.1093/jamiaopen/ooaf026
The use of large language models (LLMs) is growing for both clinicians and patients. While researchers and clinicians have explored LLMs to manage patient portal messages and reduce burnout, there is less documentation about how patients use these tools to understand clinical notes and inform decision-making. This proof-of-concept study examined the reliability and accuracy of LLMs in responding to patient queries based on an open visit note.
Author(s): Salmi, Liz, Lewis, Dana M, Clarke, Jennifer L, Dong, Zhiyong, Fischmann, Rudy, McIntosh, Emily I, Sarabu, Chethan R, DesRoches, Catherine M
DOI: 10.1093/jamiaopen/ooaf021
To assess the capacity of a bespoke artificial intelligence (AI) process to help medical writers efficiently generate quality plain language summary abstracts (PLSAs).
Author(s): McMinn, David, Grant, Tom, DeFord-Watts, Laura, Porkess, Veronica, Lens, Margarita, Rapier, Christopher, Joe, Wilson Q, Becker, Timothy A, Bender, Walter
DOI: 10.1093/jamiaopen/ooaf023
Machine learning (ML) algorithms are promising tools for managing anemia in hemodialysis (HD) patients. However, their efficacy in predicting erythropoiesis-stimulating agents (ESAs) doses remains uncertain. This study aimed to evaluate the effectiveness of a contemporary artificial intelligence (AI) model in prescribing ESA doses compared to physicians for HD patients.
Author(s): Lim, Lee-Moay, Lin, Ming-Yen, Hsu, Chan, Ku, Chantung, Chen, Yi-Pei, Kang, Yihuang, Chiu, Yi-Wen
DOI: 10.1093/jamiaopen/ooaf020
Generative AI, particularly large language models (LLMs), holds great potential for improving patient care and operational efficiency in healthcare. However, the use of LLMs is complicated by regulatory concerns around data security and patient privacy. This study aimed to develop and evaluate a secure infrastructure that allows researchers to safely leverage LLMs in healthcare while ensuring HIPAA compliance and promoting equitable AI.
Author(s): Ng, Madelena Y, Helzer, Jarrod, Pfeffer, Michael A, Seto, Tina, Hernandez-Boussard, Tina
DOI: 10.1093/jamia/ocaf005
The inclusion of social drivers of health (SDOH) into predictive algorithms of health outcomes has potential for improving algorithm interpretation, performance, generalizability, and transportability. However, there are limitations in the availability, understanding, and quality of SDOH variables, as well as a lack of guidance on how to incorporate them into algorithms when appropriate to do so. As such, few published algorithms include SDOH, and there is substantial methodological variability among [...]
Author(s): Foryciarz, Agata, Gladish, Nicole, Rehkopf, David H, Rose, Sherri
DOI: 10.1093/jamia/ocaf009
Extracting PICO elements-Participants, Intervention, Comparison, and Outcomes-from clinical trial literature is essential for clinical evidence retrieval, appraisal, and synthesis. Existing approaches do not distinguish the attributes of PICO entities. This study aims to develop a named entity recognition (NER) model to extract PICO entities with fine granularities.
Author(s): Chen, Fangyi, Zhang, Gongbo, Fang, Yilu, Peng, Yifan, Weng, Chunhua
DOI: 10.1093/jamia/ocae326