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Despite the rapid development of AI in clinical medicine, reproducibility and methodological limitations hinder its clinical utility. In response, MINimum Information for Medical AI Reporting (MINIMAR) standards were introduced to enhance publication standards and reduce bias, but their application remains unexplored. In this review, we sought to assesses the quality of reporting in AI/ML studies of cardiac amyloidosis (CA) an increasingly important cause of heart failure.

Clinical decision support (CDS) tools are critical for improving care delivery and guideline adherence but are associated with clinician burnout when inadequately designed and implemented. User-centered design (UCD) and implementation science (IS) methods are evidence-based approaches to optimizing CDS tools, but are infrequently used in part due to limited guidance on how to apply them within resource-constrained health systems.This paper focuses on pragmatic application of an integrated UCD-IS approach, demonstrating [...]

This study evaluates response rates of pharmacogenomics (PGx) nonsteroidal anti-inflammatory drugs (NSAIDs) clinical decision support (CDS) alerts at Sanford Health from May 2020 to December 2024.

Accelerate adoption of clinical research technology that obtains electronic health record (EHR) data through HL7 Fast Healthcare Interoperability Resources (FHIR).

To develop a more accurate fall prediction model within the Veterans Health Administration.

This study evaluates the performance of 7 synthetic data generation (SDG) methods-synthpop, avatar, copula, copulagan, ctgan, tvae, and the large language models-based tabula-for supporting pharmacogenetics (PGx) research.

Acute chest pain is a common presentation in the emergency department, characterized by sudden onset with high morbidity and mortality. Traditional diagnostic methods, such as computed tomography (CT) and CT angiography (CTA), are often time-consuming and fail to meet the urgent need for rapid triage in emergency settings.

We aimed to evaluate the zero-shot performance of open-source generative large language models (LLMs) on clinical information extraction from Dutch medical reports using the Diagnostic Report Analysis: General Optimization of NLP (DRAGON) benchmark.

Covariate-adaptive randomization algorithms (CARAs) can reduce covariate imbalance in randomized controlled trials (RCTs), but a lack of integration into Research Electronic Data Capture (REDCap) has limited their use. We developed a software pipeline to seamlessly integrate CARAs into REDCap as part of the all2GETHER study, a 2-armed RCT concerning HIV prevention.

Accurate characterization of patients with congenital heart disease is fundamental to research, outcomes reporting, quality improvement, and clinical decision-making. Here we present an approach to computing the anatomy of patients with congenital heart disease based on the whole of their diagnostic and surgical codes.