Quantifying representativeness in randomized clinical trials using machine learning fairness metrics.
We help identify subpopulations underrepresented in randomized clinical trials (RCTs) cohorts with respect to national, community-based or health system target populations by formulating population representativeness of RCTs as a machine learning (ML) fairness problem, deriving new representation metrics, and deploying them in easy-to-understand interactive visualization tools.
Author(s): Qi, Miao, Cahan, Owen, Foreman, Morgan A, Gruen, Daniel M, Das, Amar K, Bennett, Kristin P
DOI: 10.1093/jamiaopen/ooab077