Dependence of premature ventricular complexes on heart rate-it's not that simple.
Frequent premature ventricular complexes (PVCs) can lead to adverse health conditions such as cardiomyopathy. The linear correlation between PVC frequency and heart rate (as positive, negative, or neutral) on a 24-hour Holter recording has been proposed as a way to classify patients and guide treatment with beta-blockers. Our objective was to evaluate the robustness of this classification to measurement methodology, different 24-hour periods, and nonlinear dependencies of PVCs on heart [...]
Author(s): Osakwe, Adrien, Wightman, Noah, Deyell, Marc W, Laksman, Zachary, Shrier, Alvin, Bub, Gil, Glass, Leon, Bury, Thomas M
DOI: 10.1093/jamia/ocaf069