Determining molecular predictors of adverse drug reactions with causality analysis based on structure learning.
Adverse drug reaction (ADR) can have dire consequences. However, our current understanding of the causes of drug-induced toxicity is still limited. Hence it is of paramount importance to determine molecular factors of adverse drug responses so that safer therapies can be designed.
Author(s): Liu, Mei, Cai, Ruichu, Hu, Yong, Matheny, Michael E, Sun, Jingchun, Hu, Jun, Xu, Hua
DOI: 10.1136/amiajnl-2013-002051