Surrogate-assisted feature extraction for high-throughput phenotyping.
Phenotyping algorithms are capable of accurately identifying patients with specific phenotypes from within electronic medical records systems. However, developing phenotyping algorithms in a scalable way remains a challenge due to the extensive human resources required. This paper introduces a high-throughput unsupervised feature selection method, which improves the robustness and scalability of electronic medical record phenotyping without compromising its accuracy.
Author(s): Yu, Sheng, Chakrabortty, Abhishek, Liao, Katherine P, Cai, Tianrun, Ananthakrishnan, Ashwin N, Gainer, Vivian S, Churchill, Susanne E, Szolovits, Peter, Murphy, Shawn N, Kohane, Isaac S, Cai, Tianxi
DOI: 10.1093/jamia/ocw135