Data science and artificial intelligence to improve clinical practice and research.
Author(s): Ohno-Machado, Lucila
DOI: 10.1093/jamia/ocy136
Author(s): Ohno-Machado, Lucila
DOI: 10.1093/jamia/ocy136
The Objective Structured Assessment of Debriefing (OSAD) is an evidence-based, 8-item tool that uses a behaviorally anchored rating scale in paper-based form to evaluate the quality of debriefing in medical education. The objective of this project was twofold: 1) to create an easy-to-use electronic format of the OSAD (eOSAD) in order to streamline data entry; and 2) to pilot its use on videoed debriefings.
Author(s): Zamjahn, John B, Baroni de Carvalho, Raquel, Bronson, Megan H, Garbee, Deborah D, Paige, John T
DOI: 10.1093/jamia/ocy113
Legislation aimed at increasing the use of a health information exchange (HIE) in healthcare has excluded long-term care facilities, resulting in a vulnerable patient population that can benefit from the improvement of communication and reduction of waste.
Author(s): Kruse, Clemens Scott, Marquez, Gabriella, Nelson, Daniel, Palomares, Olivia
DOI: 10.1055/s-0038-1670651
Standards such as the Logical Observation Identifiers Names and Codes (LOINC®) are critical for interoperability and integrating data into common data models, but are inconsistently used. Without consistent mapping to standards, clinical data cannot be harmonized, shared, or interpreted in a meaningful context. We sought to develop an automated machine learning pipeline that leverages noisy labels to map laboratory data to LOINC codes.
Author(s): Parr, Sharidan K, Shotwell, Matthew S, Jeffery, Alvin D, Lasko, Thomas A, Matheny, Michael E
DOI: 10.1093/jamia/ocy110
The gold standard for diagnosing sleep disorders is polysomnography, which generates extensive data about biophysical changes occurring during sleep. We developed the National Sleep Research Resource (NSRR), a comprehensive system for sharing sleep data. The NSRR embodies elements of a data commons aimed at accelerating research to address critical questions about the impact of sleep disorders on important health outcomes.
Author(s): Zhang, Guo-Qiang, Cui, Licong, Mueller, Remo, Tao, Shiqiang, Kim, Matthew, Rueschman, Michael, Mariani, Sara, Mobley, Daniel, Redline, Susan
DOI: 10.1093/jamia/ocy064
Standard approaches for large scale phenotypic screens using electronic health record (EHR) data apply thresholds, such as ≥2 diagnosis codes, to define subjects as having a phenotype. However, the variation in the accuracy of diagnosis codes can impair the power of such screens. Our objective was to develop and evaluate an approach which converts diagnosis codes into a probability of a phenotype (PheProb). We hypothesized that this alternate approach for [...]
Author(s): Sinnott, Jennifer A, Cai, Fiona, Yu, Sheng, Hejblum, Boris P, Hong, Chuan, Kohane, Isaac S, Liao, Katherine P
DOI: 10.1093/jamia/ocy056
Electronic health records (EHRs) are transforming the way health care is delivered. They are central to improving the quality of patient care and have been attributed to making health care more accessible, reliable, and safe. However, in recent years, evidence suggests that specific features and functions of EHRs can introduce new, unanticipated patient safety concerns that can be mitigated by safe configuration practices.
Author(s): Dhillon-Chattha, Pritma, McCorkle, Ruth, Borycki, Elizabeth
DOI: 10.1055/s-0038-1675210
Surveillance for surgical site infections (SSIs) after ambulatory surgery in children requires a detailed manual chart review to assess criteria defined by the National Health and Safety Network (NHSN). Electronic health records (EHRs) impose an inefficient search process where infection preventionists must manually review every postsurgical encounter ( 30 days). Using text mining and business intelligence software, we developed an information foraging application, the SSI Workbench, to visually present which [...]
Author(s): Karavite, Dean J, Miller, Matthew W, Ramos, Mark J, Rettig, Susan L, Ross, Rachael K, Xiao, Rui, Muthu, Naveen, Localio, A Russell, Gerber, Jeffrey S, Coffin, Susan E, Grundmeier, Robert W
DOI: 10.1055/s-0038-1675179
It is unclear to what extent simulated versions of real data can be used to assess potential value of new biomarkers added to prognostic risk models. Using data on 4522 women and 3969 men who contributed information to the Framingham CVD risk prediction tool, we develop a simulation model that allows assessment of the added contribution of new biomarkers. The simulated model matches closely the one obtained using real data [...]
Author(s): Pencina, Karol M, D'Agostino, Ralph B, Vasan, Ramachandran S, Pencina, Michael J
DOI: 10.1093/jamia/ocy108
Limited data are available on the correlation of mHealth features and statistically significant outcomes. We sought to identify and analyze: types and categories of features; frequency and number of features; and relationship of statistically significant outcomes by type, frequency, and number of features.
Author(s): Donevant, Sara Belle, Estrada, Robin Dawson, Culley, Joan Marie, Habing, Brian, Adams, Swann Arp
DOI: 10.1093/jamia/ocy104