Evaluation of trajectory analysis for disease risk assessment: a scoping review.
Increasingly, structured longitudinal electronic health records (EHRs) are being harnessed to predict risk of having present but as yet undetected disease by analyzing "patient trajectories." Trajectory studies explore clinical event associations, characterize disease trajectories, and enhance risk prediction. This scoping review assesses study characteristics and objectives, identifies model types, and appraises model performance and reporting.
Author(s): Pollington, Freya, Denaxas, Spiros C, Li, Kezhi, Thygesen, Johan H, Lyratzopoulos, Georgios, White, Becky
DOI: 10.1093/jamia/ocaf208