Informatics impact requires effective, scalable tools and standards-based infrastructure.
Author(s): Bakken, Suzanne
DOI: 10.1093/jamia/ocaa187
Author(s): Bakken, Suzanne
DOI: 10.1093/jamia/ocaa187
This manuscript reviews the current state of veterinary medical electronic health records and the ability to aggregate and analyze large datasets from multiple organizations and clinics. We also review analytical techniques as well as research efforts into veterinary informatics with a focus on applications relevant to human and animal medicine. Our goal is to provide references and context for these resources so that researchers can identify resources of interest and [...]
Author(s): Lustgarten, Jonathan L, Zehnder, Ashley, Shipman, Wayde, Gancher, Elizabeth, Webb, Tracy L
DOI: 10.1093/jamiaopen/ooaa005
The study sought to explore information needs arising from a gap in clinicians' knowledge that is not met by current evidence and identify possible areas of use and target groups for a future clinical decision support system (CDSS), which will guide clinicians in cases where no evidence exists.
Author(s): Ostropolets, Anna, Chen, RuiJun, Zhang, Linying, Hripcsak, George
DOI: 10.1093/jamiaopen/ooaa012
Our primary objectives were to examine adherence rates across two technologies (e-prescribing software and smart pill bottle) with cross-validation from alert-triggered messaging within the patient electronic health record (EHR) portal and to explore the benefits and challenges faced by atrial fibrillation (AF) patients in using a smart pill bottle.
Author(s): Toscos, Tammy, Drouin, Michelle, Pater, Jessica A, Flanagan, Mindy, Wagner, Shauna, Coupe, Amanda, Ahmed, Ryan, Mirro, Michael J
DOI: 10.1093/jamiaopen/ooaa007
To describe a configurable mobile health (mHealth) framework for integration of physiologic and environmental sensors to be used in studies focusing on the domain of pediatric asthma.
Author(s): Bui, Alex A T, Hosseini, Anahita, Rocchio, Rose, Jacobs, Nate, Ross, Mindy K, Okelo, Sande, Lurmann, Fred, Eckel, Sandrah, Dzubur, Eldin, Dunton, Genevieve, Gilliland, Frank, Sarrafzadeh, Majid, Habre, Rima
DOI: 10.1093/jamiaopen/ooaa011
Phenotypes are the result of the complex interplay between environmental and genetic factors. To better understand the interactions between chemical compounds and human phenotypes, and further exposome research we have developed "phexpo," a tool to perform and explore bidirectional chemical and phenotype interactions using enrichment analyses. Phexpo utilizes gene annotations from 2 curated public repositories, the Comparative Toxicogenomics Database and the Human Phenotype Ontology. We have applied phexpo in 3 [...]
Author(s): Hawthorne, Christopher, Simpson, David A, Devereux, Barry, López-Campos, Guillermo
DOI: 10.1093/jamiaopen/ooaa023
Clinicians are increasingly being asked to heed and follow the guidance provided by "best practice advisories." Such advisories, often in the form of electronic reminders or alerts, are meant to increase the efficiency and effectiveness of evidence-based medical practice. However, we argue that best practice advisories can sometimes be infused with stakeholder bias, even if inadvertently. We specifically argue that best practice advisory biases can occur when an advisory is [...]
Author(s): Baird, Aaron, Kibbe, Bryan, Lesandrini, Jason
DOI: 10.1093/jamiaopen/ooaa018
Author(s): Bakken, Suzanne
DOI: 10.1093/jamia/ocaa132
The goal of this study is to develop a robust Time Event Ontology (TEO), which can formally represent and reason both structured and unstructured temporal information.
Author(s): Li, Fang, Du, Jingcheng, He, Yongqun, Song, Hsing-Yi, Madkour, Mohcine, Rao, Guozheng, Xiang, Yang, Luo, Yi, Chen, Henry W, Liu, Sijia, Wang, Liwei, Liu, Hongfang, Xu, Hua, Tao, Cui
DOI: 10.1093/jamia/ocaa058
Large observational data networks that leverage routine clinical practice data in electronic health records (EHRs) are critical resources for research on coronavirus disease 2019 (COVID-19). Data normalization is a key challenge for the secondary use of EHRs for COVID-19 research across institutions. In this study, we addressed the challenge of automating the normalization of COVID-19 diagnostic tests, which are critical data elements, but for which controlled terminology terms were published [...]
Author(s): Dong, Xiao, Li, Jianfu, Soysal, Ekin, Bian, Jiang, DuVall, Scott L, Hanchrow, Elizabeth, Liu, Hongfang, Lynch, Kristine E, Matheny, Michael, Natarajan, Karthik, Ohno-Machado, Lucila, Pakhomov, Serguei, Reeves, Ruth Madeleine, Sitapati, Amy M, Abhyankar, Swapna, Cullen, Theresa, Deckard, Jami, Jiang, Xiaoqian, Murphy, Robert, Xu, Hua
DOI: 10.1093/jamia/ocaa145