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With health care policy directives advancing value-based care, risk assessments and management have permeated health care discourse. The conventional problem-based infrastructure defines what data are employed to build this discourse and how it unfolds. Such a health care model tends to bias data for risk assessment and risk management toward problems and does not capture data about health assets or strengths. The purpose of this article is to explore and [...]

To demonstrate the feasibility of pragmatic clinical trials comparing the effectiveness of treatments using the electronic medical record (EMR) and an adaptive assignment design.

Most determinants of health originate from the "contexts" in which we live, which has remained outside the confines of the U.S. healthcare system. This issue has left providers unprepared to operate with an ample understanding of the challenges patients may face beyond their purview. The recent shift to value-based care and increasing prevalence of Electronic Health Record (EHR) systems provide opportunities to incorporate upstream contextual factors into care. We discuss [...]

Computing patients' similarity is of great interest in precision oncology since it supports clustering and subgroup identification, eventually leading to tailored therapies. The availability of large amounts of biomedical data, characterized by large feature sets and sparse content, motivates the development of new methods to compute patient similarities able to fuse heterogeneous data sources with the available knowledge.