P2T2: Protein Panoramic annoTation Tool for the interpretation of protein coding genetic variants.
Genomic data are prevalent, leading to frequent encounters with uninterpreted variants or mutations with unknown mechanisms of effect. Researchers must manually aggregate data from multiple sources and across related proteins, mentally translating effects between the genome and proteome, to attempt to understand mechanisms.
Author(s): DeVoe, Elias, Oliver, Gavin R, Zenka, Roman, Blackburn, Patrick R, Cousin, Margot A, Boczek, Nicole J, Kocher, Jean-Pierre A, Urrutia, Raul, Klee, Eric W, Zimmermann, Michael T
DOI: 10.1093/jamiaopen/ooab065