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Federated research networks, like Evolve to Next-Gen Accrual of patients to Clinical Trials (ENACT), aim to facilitate medical research by exchanging electronic health record (EHR) data. However, poor data quality can hinder this goal. While networks typically set guidelines and standards to address this problem, we developed an organically evolving, data-centric method using patient counts to identify data quality issues, applicable even to sites not yet in the network.

Patients referred for specialized care often arrive with outside medical records (OMRs) compiled into multi-report PDFs that include imaging, pathology, and clinical notes in unstructured formats. Reviewing these records is time consuming and mentally taxing, increasing the risk of delayed care, clinician frustration, and missed information affecting quality of care. This study aimed to automate the segmentation, classification, and date extraction of scanned OMRs, with a focus on records relevant [...]

To verify that federated genomic study sites applied identical preprocessing pipelines without disclosing raw genotypes.

Echocardiography and cardiac catheterization reports capture important clinical assessment information of cardiac function and disease severity. This study explores using open-source transformer-based language models (LMs) that are run locally within an institutional environment as a privacy-preserving alternative to external API-based large LM to systematically extract clinical data from unstructured echocardiography and cardiac catheterization reports, aiming to improve data accessibility for research and patient care.

To test the impact of visual summaries of blood pressure (BP) data (eg, stoplight and gradient displays), within the context of a patient-facing digital application connected to the EHR, on patient judgments about hypertension control.

We evaluated the data requirement for modern AI tools to outperform simpler models in predicting short-term mortality in over 500 000 patients with hemodialysis-dependent kidney failure.

To assess patient awareness, trust, perceived benefits, and risks of artificial intelligence (AI) in clinical care within an urban safety-net health system.

To address the gap between artificial intelligence (AI) model development and clinical implementation by developing a machine-learning model to predict cochlear implant (CI) eligibility based on routine hearing tests, while illustrating 3 practical lessons: reformulation for clinical utility, selection of problem-specific metrics, and handling input data variability.

To develop and validate a prespecified logistic model for detecting mild cognitive impairment (MCI) using MyCog Mobile, a self-administered smartphone-based screening application, and to evaluate a structured simplification that reduces patient burden while maintaining diagnostic accuracy.

Medical product safety surveillance efforts, whether using electronic health record (EHR) or claims data, typically rely on structured codes. Utilizing unstructured EHR data, particularly information extracted from clinical text through natural language processing (NLP), enriches information available for data mining, phenotyping, and surveillance. To assess overlapping and distinct information across structured and unstructured EHR data, we mapped both to a common vocabulary (Medical Dictionary for Regulatory Activities, MedDRA). We assess [...]