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To address algorithmic bias in clinical prediction models related to the timing of diagnosis, we evaluated the efficacy of mixture cure models that integrate time-to-event and binary classification frameworks to predict diagnoses.

To identify causal mechanisms driving variations in the impact of rehabilitation treatments on stroke survivors' independence improvement during rehabilitation inpatient stays.

Sharing clinical data for research that is both collaborative and privacy-preserving remains a challenge. Differential privacy (DP) offers a solution by introducing noise to query results. Using the PrivateSQL DP platform, this study assesses the resulting utility of differentially private data at different levels of aggregation through analyses of COVID-19 pandemic associations with new cancer diagnosis counts (NCCs).

Clinician perspectives on machine learning and artificial intelligence (ML/AI) vary with discipline. However, fewer studies describe patient perspectives and address medical situations that require rapid decisions with durable consequences for patient outcomes. This study characterized perspectives (qualitatively) and sentiment (quantitatively) regarding the use of ML/AI for patient management in neurological emergencies.

Critically ill patients are managed with complex medication regimens that require medication management to optimize safety and efficacy. When performed by a critical care pharmacist (CCP), discrete medication management activities are termed medication interventions. The ability to define CCP workflow and intervention timeliness depends on the ability to predict the medication management needs of individual intensive care unit (ICU) patients. The purpose of this study was to develop prediction models [...]

A point-of-care resource is required to support Registered Dietitian Nutritionists (RDNs) in providing comprehensive culturally-tailored nutrition services. This study aims to describe the iterative development and testing of a comprehensive nutrition assessment tool as part of a novel web-based platform to Support Personalized and Inclusive Cuisines in Environments for Healthcare (SPICE-Healthcare).

Health information exchanges (HIE), tools that electronically share clinical data across healthcare organizations, provide the opportunity to improve patient care. While widely available, HIE is utilized in only 2%-10% of patient encounters. Few studies have explored current barriers to use. The goal of this study was to evaluate current clinician perspectives on HIE and barriers to use at the point of care.

This study evaluates the performance and deployment feasibility of a machine learning (ML) model to identify adult-onset type 1 diabetes (T1D) initially coded as type 2 on electronic medical records (EMRs) from a health information exchange (HIE). To our knowledge, this is the first evaluation of such a model on real-world HIE data.

To implementation an automated multi-institutional pipeline that delivers breast-cancer risk integrated with polygenic risk scores, monogenic variants, family history, and clinical factors, emphasizing operational challenges and their solutions.

To evaluate predictive diagnostic performance of open- and closed-source large language models (LLMs) in emergency medicine, addressing the urgent need for innovative clinical decision support tools amid rising patient volumes and staffing shortages.