Deep significance clustering: a novel approach for identifying risk-stratified and predictive patient subgroups.
Deep significance clustering (DICE) is a self-supervised learning framework. DICE identifies clinically similar and risk-stratified subgroups that neither unsupervised clustering algorithms nor supervised risk prediction algorithms alone are guaranteed to generate.
Author(s): Huang, Yufang, Liu, Yifan, Steel, Peter A D, Axsom, Kelly M, Lee, John R, Tummalapalli, Sri Lekha, Wang, Fei, Pathak, Jyotishman, Subramanian, Lakshminarayanan, Zhang, Yiye
DOI: 10.1093/jamia/ocab203