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The Enhanced EHR-facilitated Cancer Symptom Control (E2C2) Trial is a pragmatic trial testing a collaborative care approach for managing common cancer symptoms. There were challenges in identifying cancer site and metastatic status.This study compares three different approaches to determine cancer site and six strategies for identifying the presence of metastasis using EHR and cancer registry data.The E2C2 cohort included 50,559 patients seen in the medical oncology clinics of a large [...]

Human immunodeficiency virus (HIV) remains a significant global health challenge, especially in Europe, including Italy, where it affects thousands. Antiretroviral therapy (ART) has turned HIV into a manageable chronic condition, improving the quality of life and life expectancy for people living with HIV (PLWH). Enhancing health-related quality of life (HRQoL) is essential, as it positively influences therapy adherence.The objective of the study was to evaluate the impact of the AURORA [...]

Adoption of electronic health record (EHR)-based clinical decision support tools in community-based health centers might increase the provision of indicated cancer screening orders. We examined: (1) if the use of the care gaps smartset (CGS), an EHR tool that expedites ordering care, is associated with colorectal/cervical cancer (CRC/CVC) screening order rates; and (2) how selected implementation strategies, barriers, and facilitators impact CGS use.Within a sequential mixed methods design, we used [...]

Interruptive alerts in clinical decision support (CDS) systems are intended to guide clinicians in making informed decisions and adhering to best practices. However, these alerts can often become a source of frustration, contributing to alert fatigue and clinician burnout. Traditionally, an alert's burden is often assessed by evaluating the total number of times it is seen by end-users, which can overlook the true impact of highly interruptive workflows. This study [...]

Effective data management is critical in medical informatics research, ensuring the success and integrity of clinical studies. However, students often lack comprehensive training in this area, highlighting the need for tailored educational programs.

This study aimed to demonstrate real-world use of the Making Electronic Data More Available for Research and Public Health (MedMorph) Reference Architecture (RA) for automated exchange of hepatitis C-related data for public health surveillance and research using Fast Healthcare Interoperability Resources (FHIR).

The use of electronic health records (EHRs) in research demands robust and interoperable systems. By linking biorepositories to EHR algorithms, researchers can efficiently identify cases and controls for large observational studies (e.g., genome-wide association studies). This is critical for ensuring efficient and cost-effective research. However, the lack of standardized metadata and algorithms across different EHRs complicates their sharing and application. Our study presents an example of a successful implementation and [...]

The "cancer risk calculator" mobile application aims to inform patients about their personal risks of cancer and the risk factors influencing said risks. The present analysis examines the responses to a questionnaire submitted by oncology patients treated with radiotherapy or their family members.

This study aimed to develop a measure of health information exchange (HIE) for characterizing the density of inter-hospital HIE connections and identify regional characteristics associated with HIE network density.