Evidence-based medicine on FHIR augments the standards-based approach to digital health research.
Author(s): Alper, Brian S, Dehnbostel, Joanne, Lehmann, Harold
DOI: 10.1093/jamia/ocag024
Author(s): Alper, Brian S, Dehnbostel, Joanne, Lehmann, Harold
DOI: 10.1093/jamia/ocag024
Physician and advanced practice provider (APP) well-being is a critical focus in healthcare. Emerging technology such as generative artificial intelligence (GAI) scribes reduces physician and APP administrative burden created by electronic health records. Early adopters of this technology have demonstrated promising improvements in clinical documentation, well-being, and cognitive load. However, further exploration across professional roles is warranted.
Author(s): Schneider, Kathryn R, Swann-Thomsen, Hillary E, Ribbens, Terry G, Bahnmaier, Lucas A, Satterfield, Trevor, Pullicar, Reme, Soni, Neeraj
DOI: 10.1093/jamia/ocag005
Author(s): Zablah, Jose, Molina, Yolly, Garcia Loureiro, Antonio
DOI: 10.1093/jamia/ocag023
Author(s): Cheng, Weihao
DOI: 10.1093/jamia/ocag022
Our study aims to assess the time-cost burden reduction of transitioning from manual case reporting to electronic case reporting (eCR) for COVID-19 among healthcare organizations (HCOs) over a 1-year period.
Author(s): Rincón-Guevara, Oscar, Olorukooba, Abdulhakeem A, Eau, Grace, Ritchey, Matthew D, Conn, Laura A, Knicely, Kimberly
DOI: 10.1093/jamia/ocag011
Efficient exchange of health information requires consistent representation of clinical concepts across laboratories, hospitals, and public health systems. LOINC supports this interoperability by standardizing laboratory test codes, but mapping remains difficult when datasets are incomplete, inconsistently formatted, or structurally diverse. These challenges often create a mismatch between algorithmic performance in controlled settings and real-world deployment. This study aimed to develop a biomedical natural language processing (NLP) approach for mapping heterogeneous [...]
Author(s): Naliyatthaliyazchayil, Parvati, Sangam, Venkat Ramana, Amlung, Joseph, Kanter, Andrew S, Purkayastha, Saptarshi, Payne, Jonathan
DOI: 10.1093/jamia/ocag010
To comprehensively evaluate the validity of International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) codes for both prevalent diagnoses and less common diseases, and to assess the performance of a large language model (LLM)-based system in validating these codes.
Author(s): Wang, Yichen, Song, Yilin, Siu, Rex, Nimma, Induja R, Yan, Yan, Savage, Thomas R, Wang, Yiming, Li, Zhichen, Ramai, Daryl, Wang, Jiale, Badurdeen, Dilhana, Tao, Cui, Kumbhari, Vivek, Huang, Yuting
DOI: 10.1093/jamia/ocag008
The MTXPK.org webtool facilitates model-informed supportive care and glucarpidase use in patients receiving high-dose methotrexate, but its reliance on manual data entry limits workflow integration. We aimed to highlight how translational informatics can advance, automate, and enhance the usability of clinical decision support tools by embedding MTXPK.org within the electronic health record (EHR).
Author(s): Taylor, Zachary L, Punt, Nieko, Jenkinson, Chris, Vidonish, Bill, Young, Jennifer, O'Brien, Maureen M, Ramsey, Laura B
DOI: 10.1093/jamiaopen/ooag057
Implementing biomedical informatics (BMI) tools and applications into clinical and other settings remains a significant challenge. Unintended consequences remain common post-implementation. This paper addresses the above issue by integrating systems thinking and implementation science approaches to support health information technology (HIT) implementation.
Author(s): Kuziemsky, Craig E, Ozkaynak, Mustafa, Unertl, Kim M, Haque, Saira
DOI: 10.1093/jamiaopen/ooag023
Ohio has been severely impacted by the opioid crisis, with opioid overdose (OD) death rates exceeding national averages. Accurate OD death prediction supports proactive prevention and treatment allocation. Existing methods often focus on ZIP Code Tabulation Area (ZCTA)-level prediction for small-area resource allocation; however, performance at this resolution is poor due to substantial fluctuations in OD death counts, which introduce noise. This raises a critical methodological question: what is the [...]
Author(s): Chen, Xianhui, Yin, Changchang, Myers, John V, Slover, Brandon, Thomas, Neena, Marks, Charles, Kim, Joanne, Fernández, Soledad, Whitley, Penn, Fareed, Naleef, Zhang, Ping
DOI: 10.1093/jamiaopen/ooag063