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Clinicians' occupational fatigue can lead to suboptimal decisions that do not align with evidence-based guidelines or patient needs.

This study aimed to describe human-centered design of clinical decision support (CDS) for children with metabolic diseases at high risk of rapid decompensation, assess the influence of CDS on care processes and patient outcomes, and share insights from the implementation.A CDS was designed in collaboration with pediatric genetics experts to provide accelerated triage and recommend dextrose-containing fluids for patients metabolic conditions. Formative usability testing was conducted with emergency department (ED) [...]

Chemoprophylaxis reduces the risk of hospital-acquired venous thromboembolism (VTE), but is not reliably ordered. Our institution created a clinical decision support (CDS) interruptive alert to remind clinicians to order VTE chemoprophylaxis when it is missing for qualifying inpatients. Unfortunately, this alert has required repeated modifications to ensure accurate logic, and continues to generate negative feedback from users.This study aimed to describe multiple failures in the development and postdeployment optimization of [...]

The goal of national interoperability is to improve care quality and decrease administrative burden and costs. Patients, providers, and other stakeholders are increasingly concerned that indiscriminate sharing of data may have deleterious, permanent consequences, as well as fail to provide granular control over the sharing of individual health data. Data segmentation and consent standards to date have been limited in scope and implementation, which has hindered efforts to scale data [...]

Traditional early warning systems (EWS) have shown uncertain efficacy in real-world settings. More recently, machine learning models like the Epic Deterioration Index (DTI) have been developed, promising greater accuracy. Recognizing the potential of DTI, but also the pervasive issue of alert fatigue with interruptive (i.e., pop-up) EWS alerts, our institution implemented a DTI-enabled EWS with passive alerts (colored icons visible in prespecified locations within the electronic health record). We hypothesized [...]

Studies on symptom concordance between patients and their caregivers often use cross-sectional designs, which may fail to capture the longitudinal, dynamic symptom experience. The Behavioral and Environmental Sensing and Intervention for Cancer (BESI-C) is a remote health monitoring system that utilizes smartwatches and ecological momentary assessments (EMAs) to empower patients and caregivers to monitor and manage cancer pain at home. BESI-C collects real-time symptom data in naturalistic settings, enabling longitudinal [...]

Aging populations strain health care systems. Assisted Living Technologies (ALTs) emerge as a potential solution for promoting independent living among older adults. However, the real-world effect of ALTs remains unclear.This study explores benefits and challenges (anticipated and unanticipated) of ALTs for older adults and informal caregivers across three aged care settings (residential aged care facilities [RACFs], retirement villages [RVs], and home-dwelling communities [HDCs]) in Australia.Three ALTs (fall detection sensors, sleep [...]

As healthcare delivery becomes increasingly digital, nursing informatics knowledge has become essential for nurses to participate effectively in digitally enabled healthcare environments. The Canadian Association of Schools of Nursing (CASN) released updated nursing informatics entry-to-practice competencies in 2025 to inform nursing education in Canada. However, the integration of informatics knowledge and content into nursing curricula and professional practice education remains inconsistent. Mapping the teaching strategies used by nursing educators to [...]

To enable users with modest technical background to perform biomedical natural language processing (NLP).

Electronic patient-reported outcome measures (ePROMs) can improve care for people with cancer, but effectiveness hinges on well-supported integration in clinical settings.We evaluated clinician use of specific clinical decision support (CDS) tools in the electronic health record (EHR) designed to facilitate timely, clinically appropriate responses to ePROM scores for six symptoms commonly experienced by cancer patients.The parent pragmatic trial, which took place at Mayo Clinic (Rochester, Minnesota, United States) and its [...]