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The number of ethical frameworks designed to guide artificial intelligence (AI) use has grown substantially over the past decade, yet their real-world effect remains unclear. We aimed to synthesize existing evidence to analyze the practical impact of AI ethics frameworks (AIEFs) operationalized in healthcare.

To address the challenges of data heterogeneity and manual feature engineering in clinical predictive modeling, we introduce FHIR-Former, an open-source framework integrating Fast Healthcare Interoperability Resources (FHIR) with large language models (LLMs) to automate and standardize clinical prediction tasks.

To evaluate the accuracy, computational cost, and portability of a new natural language processing (NLP) method for extracting medication information from clinical narratives.

Acute otitis media (AOM) is a leading cause of pediatric antibiotic overuse. Safety Net Antibiotic Prescriptions (SNAPs) are recommended for antibiotic stewardship but are difficult to identify due to lack of structured documentation.

In medical research and education, generative artificial intelligence/machine learning (AI/ML) models to synthesize artificial medical data can enable the sharing of high-quality data while preserving the privacy of patients. Given that such data is often high-dimensional, a relevant consideration is whether to synthesize the entire dataset when only a task-relevant subset is needed. This study evaluates how the number of variables in training impacts fidelity, utility, and privacy of the [...]

Longitudinal data in electronic health records (EHRs) represent an individual's clinical history through a sequence of codified concepts, including diagnoses, procedures, medications, and laboratory tests. Generative pretrained transformers (GPT) can leverage this data to predict future events. While fine-tuning of these models can enhance task-specific performance, it becomes costly when applied to many clinical prediction tasks. In contrast, a pretrained foundation model can be used in zero-shot forecasting setting, offering [...]

To understand whether patients prefer chatbots for certain tasks in healthcare, and their motivations for doing so, recognizing that chatbots are already assisting patients with various healthcare tasks.

Health information exchanges (HIE), tools that electronically share clinical data across healthcare organizations, provide the opportunity to improve patient care. While widely available, HIE is utilized in only 2%-10% of patient encounters. Few studies have explored current barriers to use. The goal of this study was to evaluate current clinician perspectives on HIE and barriers to use at the point of care.

Overuse and misuse of antibiotics is an urgent health care problem and one of the key factors in antibiotic resistance. Validated clinical prediction rules have shown effectiveness in guiding providers to an appropriate diagnosis and identifying when antibiotics are the recommended choice for treatment.We aimed to study the relative ability of registered nurses using clinical prediction rules to guide the management of acute respiratory infections in a simulated environment compared [...]

This quality improvement study implemented and prospectively examined user engagement with an artificial intelligence (AI)-powered clinical trial knowledge management application at an NCI-designated comprehensive cancer center.