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Human-centered design (HCD) methods in machine learning generally focus on workflow, user interfaces, and data visualizations, but there is the potential to apply these methods to inform the model development and testing process.This study aimed to demonstrate the potential of HCD methods to support the design and testing of machine learning models developed for clinical decision-making.In preparing for formative user testing of clinician facing representations of a machine learning model [...]

Electronic health record (EHR) systems have become integral to hospital-based care, with studies showing physicians spending significant time interfacing with these systems. While EHR interactions are necessary for patient care, understanding usage patterns can identify opportunities for system optimization and workflow improvement. Previous studies have focused on outpatient settings, making this study among the first to comprehensively analyze inpatient EHR interaction patterns.This study aims to characterize EHR utilization patterns among [...]

To improve the identification of patients with health-related social needs (HRSNs) in the emergency department (ED), we developed and integrated a risk prediction score into an existing Fast Healthcare Interoperability Resources (FHIR)-based clinical decision support (CDS).

To determine whether a novel digital tool, the Community Vulnerability Compass (CVC), built using large datasets, can accurately measure neighborhood- and individual-level social determinants of health (SDOH) at scale. Existing SDOH indexes fall short of this dual requirement.

Acute kidney injury (AKI) is common in intensive care unit (ICU) patients and is associated with high mortality, prolonged ICU stays, and increased costs. Early prediction is crucial for timely intervention and improved outcomes. Various prediction models, including machine learning, deep learning, and dynamic prediction frameworks, have been developed, but their modeling approaches, data utilization, and clinical applicability require further investigation. This review comprehensively assesses the modeling methods, data utilization [...]

Clinicians currently make decisions about placing an intracranial pressure (ICP) monitor in children with traumatic brain injury (TBI) without the benefit of an accurate clinical decision support tool. The goal of this study was to develop and validate a model that predicts placement of an ICP monitor and updates as new information becomes available.

Emerging efforts to identify patients at risk of suicide have focused on the development of predictive algorithms for use in healthcare settings. We address a major challenge in effective risk modeling in healthcare settings with insufficient data with which to create and apply risk models. This study aimed to improve risk prediction using transfer learning or data fusion by incorporating risk information from external data sources to augment the data [...]

Common Data Elements (CDEs) standardize data collection and sharing across studies, enhancing data interoperability and improving research reproducibility. However, implementing CDEs presents challenges due to the broad range and variety of data elements. This study aims to develop a CDE mapping tool to bridge the gap between local data elements and National Institutes of Health (NIH) CDEs.

To determine how much of the current biomedical literature would be flagged or require modification in relation to the presence of terms from leaked lists prepared by the Centers for Disease Control (CDC), the National Science Foundation (NSF), and the National Security Administration (NSA) in early 2025.

Unlocking clinical information embedded in clinical notes has been hindered to a significant degree by domain-specific and context-sensitive language. Identification of note sections and structural document elements has been shown to improve information extraction and dependent downstream clinical natural language processing (NLP) tasks and applications. This study investigates the viability of a dynamic example selection prompting method to section classification using lightweight, open-source large language models (LLMs) as a practical [...]