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While performance drift of clinical prediction models is well-documented, the potential for algorithmic biases to emerge post-deployment has had limited characterization. A better understanding of how temporal model performance may shift across subpopulations is required to incorporate fairness drift into model maintenance strategies.

To determine the extent to which current large language models (LLMs) can serve as substitutes for traditional machine learning (ML) as clinical predictors using data from electronic health records (EHRs), we investigated various factors that can impact their adoption, including overall performance, calibration, fairness, and resilience to privacy protections that reduce data fidelity.

(1) Describe the evolution of Health Information Exchanges (HIEs) into Health Data Utilities (HDUs); (2) Provide motivation for HDUs as a public strategic investment target.

Direct electronic access to multiple electronic health record (EHR) systems through patient portals offers a novel avenue for decentralized research. Given the critical value of patient characterization, we sought to compare computable evaluation of health conditions from patient-portal EHR against the traditional self-report.

This study aimed to develop a novel multi-stage self-supervised learning model tailored for the accurate classification of optical coherence tomography (OCT) images in ophthalmology reducing reliance on costly labeled datasets while maintaining high diagnostic accuracy.

This study assesses the abilities of 2 large language models (LLMs), GPT-4 and BioMistral 7B, in responding to patient queries, particularly concerning rare diseases, and compares their performance with that of physicians.

Developing equitable, sustainable informatics solutions is key to scalability and long-term success for projects in the global health informatics (GHI) domain. This paper presents key strategies for incorporating principles of health equity in the GHI project lifecycle.

Digital health equity, the opportunity for all to engage with digital health tools to support good health outcomes, is an emerging priority across the world. The field of digital health equity would benefit from a comprehensive and systematic understanding of digital health, digital equity, and health equity, with a focus on real-world applications. We conducted a scoping review to identify and describe published frameworks and concepts relevant to digital health [...]