The Tendril Plot-a novel visual summary of the incidence, significance and temporal aspects of adverse events in clinical trials.
In contrast to efficacy, safety hypotheses of clinical trials are not always pre-specified, and therefore, the safety interpretation work of a trial tends to be more exploratory, often reactive, and the analysis more statistically and graphically challenging.
Author(s): Karpefors, Martin, Weatherall, James
DOI: 10.1093/jamia/ocy016