Consideration of bias in data sources and digital services to advance health equity.
Author(s): Bakken, Suzanne
DOI: 10.1093/jamia/ocac074
Author(s): Bakken, Suzanne
DOI: 10.1093/jamia/ocac074
Sepsis has a high rate of 30-day unplanned readmissions. Predictive modeling has been suggested as a tool to identify high-risk patients. However, existing sepsis readmission models have low predictive value and most predictive factors in such models are not actionable.
Author(s): Amrollahi, Fatemeh, Shashikumar, Supreeth P, Meier, Angela, Ohno-Machado, Lucila, Nemati, Shamim, Wardi, Gabriel
DOI: 10.1093/jamia/ocac060
This systematic review aims to assess how information from unstructured text is used to develop and validate clinical prognostic prediction models. We summarize the prediction problems and methodological landscape and determine whether using text data in addition to more commonly used structured data improves the prediction performance.
Author(s): Seinen, Tom M, Fridgeirsson, Egill A, Ioannou, Solomon, Jeannetot, Daniel, John, Luis H, Kors, Jan A, Markus, Aniek F, Pera, Victor, Rekkas, Alexandros, Williams, Ross D, Yang, Cynthia, van Mulligen, Erik M, Rijnbeek, Peter R
DOI: 10.1093/jamia/ocac058
Electronic health record (EHR)-derived data are extensively used in health research. However, the pattern of patient interaction with the healthcare system can result in informative presence bias if those who have poorer health have more data recorded than healthier patients. We aimed to determine how informative presence affects bias across multiple scenarios informed by real-world healthcare utilization patterns.
Author(s): Harton, Joanna, Mitra, Nandita, Hubbard, Rebecca A
DOI: 10.1093/jamia/ocac050
To combine machine efficiency and human intelligence for converting complex clinical trial eligibility criteria text into cohort queries.
Author(s): Fang, Yilu, Idnay, Betina, Sun, Yingcheng, Liu, Hao, Chen, Zhehuan, Marder, Karen, Xu, Hua, Schnall, Rebecca, Weng, Chunhua
DOI: 10.1093/jamia/ocac051
Artificial intelligence (AI) models may propagate harmful biases in performance and hence negatively affect the underserved. We aimed to assess the degree to which data quality of electronic health records (EHRs) affected by inequities related to low socioeconomic status (SES), results in differential performance of AI models across SES.
Author(s): Juhn, Young J, Ryu, Euijung, Wi, Chung-Il, King, Katherine S, Malik, Momin, Romero-Brufau, Santiago, Weng, Chunhua, Sohn, Sunghwan, Sharp, Richard R, Halamka, John D
DOI: 10.1093/jamia/ocac052
Emerging technologies (eg, wearable devices) have made it possible to collect data directly from individuals (eg, time-series), providing new insights on the health and well-being of individual patients. Broadening the access to these data would facilitate the integration with existing data sources (eg, clinical and genomic data) and advance medical research. Compared to traditional health data, these data are collected directly from individuals, are highly unique and provide fine-grained information [...]
Author(s): Bonomi, Luca, Wu, Zeyun, Fan, Liyue
DOI: 10.1093/jamia/ocac047
Tumor registries in integrated healthcare systems (IHCS) have high precision for identifying incident cancer but often miss recently diagnosed cancers or those diagnosed outside of the IHCS. We developed an algorithm using the electronic medical record (EMR) to identify people with a history of cancer not captured in the tumor registry to identify adults, aged 40-65 years, with no history of cancer.
Author(s): Gander, Jennifer C, Maiyani, Mahesh, White, Larissa L, Sterrett, Andrew T, Güney, Brianna, Pawloski, Pamala A, DeFor, Teri, Olsen, YuanYuan, Rybicki, Benjamin A, Neslund-Dudas, Christine, Sheth, Darsheen, Krajenta, Richard, Purushothaman, Devaki, Honda, Stacey, Yonehara, Cyndee, Goddard, Katrina A B, Prado, Yolanda K, Ahsan, Habibul, Kibriya, Muhammad G, Aschebrook-Kilfoy, Briseis, Chan, Chun-Hung, Hague, Sarah, Clarke, Christina L, Thompson, Brooke, Sawyer, Jennifer, Gaudet, Mia M, Feigelson, Heather Spencer
DOI: 10.1093/jamia/ocac044
Accurate extraction of breast cancer patients' phenotypes is important for clinical decision support and clinical research. This study developed and evaluated cancer domain pretrained CancerBERT models for extracting breast cancer phenotypes from clinical texts. We also investigated the effect of customized cancer-related vocabulary on the performance of CancerBERT models.
Author(s): Zhou, Sicheng, Wang, Nan, Wang, Liwei, Liu, Hongfang, Zhang, Rui
DOI: 10.1093/jamia/ocac040
We sought to evaluate the fidelity with which the patient's clinical state is represented by the electronic health record (EHR) flow sheet vital signs data compared to a commercially available automated data aggregation platform in a pediatric cardiac intensive care unit (CICU).
Author(s): Lowry, Adam W, Futterman, Craig A, Gazit, Avihu Z
DOI: 10.1093/jamia/ocac033