What can you do with a large language model?
Author(s): Bakken, Suzanne
DOI: 10.1093/jamia/ocae106
Author(s): Bakken, Suzanne
DOI: 10.1093/jamia/ocae106
Racial disparities in kidney transplant access and posttransplant outcomes exist between non-Hispanic Black (NHB) and non-Hispanic White (NHW) patients in the United States, with the site of care being a key contributor. Using multi-site data to examine the effect of site of care on racial disparities, the key challenge is the dilemma in sharing patient-level data due to regulations for protecting patients' privacy.
Author(s): Tong, Jiayi, Shen, Yishan, Xu, Alice, He, Xing, Luo, Chongliang, Edmondson, Mackenzie, Zhang, Dazheng, Lu, Yiwen, Yan, Chao, Li, Ruowang, Siegel, Lianne, Sun, Lichao, Shenkman, Elizabeth A, Morton, Sally C, Malin, Bradley A, Bian, Jiang, Asch, David A, Chen, Yong
DOI: 10.1093/jamia/ocae075
To compare performances of a classifier that leverages language models when trained on synthetic versus authentic clinical notes.
Author(s): Litake, Onkar, Park, Brian H, Tully, Jeffrey L, Gabriel, Rodney A
DOI: 10.1093/jamia/ocae081
Herbal prescription recommendation (HPR) is a hot topic and challenging issue in field of clinical decision support of traditional Chinese medicine (TCM). However, almost all previous HPR methods have not adhered to the clinical principles of syndrome differentiation and treatment planning of TCM, which has resulted in suboptimal performance and difficulties in application to real-world clinical scenarios.
Author(s): Dong, Xin, Zhao, Chenxi, Song, Xinpeng, Zhang, Lei, Liu, Yu, Wu, Jun, Xu, Yiran, Xu, Ning, Liu, Jialing, Yu, Haibin, Yang, Kuo, Zhou, Xuezhong
DOI: 10.1093/jamia/ocae066
The timely stratification of trauma injury severity can enhance the quality of trauma care but it requires intense manual annotation from certified trauma coders. The objective of this study is to develop machine learning models for the stratification of trauma injury severity across various body regions using clinical text and structured electronic health records (EHRs) data.
Author(s): Gao, Jifan, Chen, Guanhua, O'Rourke, Ann P, Caskey, John, Carey, Kyle A, Oguss, Madeline, Stey, Anne, Dligach, Dmitriy, Miller, Timothy, Mayampurath, Anoop, Churpek, Matthew M, Afshar, Majid
DOI: 10.1093/jamia/ocae071
To investigate the consistency and reliability of medication recommendations provided by ChatGPT for common dermatological conditions, highlighting the potential for ChatGPT to offer second opinions in patient treatment while also delineating possible limitations.
Author(s): Iqbal, Usman, Lee, Leon Tsung-Ju, Rahmanti, Annisa Ristya, Celi, Leo Anthony, Li, Yu-Chuan Jack
DOI: 10.1093/jamia/ocae067
To develop and validate a natural language processing (NLP) pipeline that detects 18 conditions in French clinical notes, including 16 comorbidities of the Charlson index, while exploring a collaborative and privacy-enhancing workflow.
Author(s): Petit-Jean, Thomas, Gérardin, Christel, Berthelot, Emmanuelle, Chatellier, Gilles, Frank, Marie, Tannier, Xavier, Kempf, Emmanuelle, Bey, Romain
DOI: 10.1093/jamia/ocae069
This study focuses on refining temporal relation extraction within medical documents by introducing an innovative bimodal architecture. The overarching goal is to enhance our understanding of narrative processes in the medical domain, particularly through the analysis of extensive reports and notes concerning patient experiences.
Author(s): Knez, Timotej, Žitnik, Slavko
DOI: 10.1093/jamia/ocae059
We developed and externally validated a machine-learning model to predict postpartum depression (PPD) using data from electronic health records (EHRs). Effort is under way to implement the PPD prediction model within the EHR system for clinical decision support. We describe the pre-implementation evaluation process that considered model performance, fairness, and clinical appropriateness.
Author(s): Liu, Yifan, Joly, Rochelle, Reading Turchioe, Meghan, Benda, Natalie, Hermann, Alison, Beecy, Ashley, Pathak, Jyotishman, Zhang, Yiye
DOI: 10.1093/jamia/ocae056
Passive monitoring of touchscreen interactions generates keystroke dynamic signals that can be used to detect and track neurological conditions such as Parkinson's disease (PD) and psychomotor impairment with minimal burden on the user. However, this typically requires datasets with clinically confirmed labels collected in standardized environments, which is challenging, especially for a large subject pool. This study validates the efficacy of a self-supervised learning method in reducing the reliance on [...]
Author(s): Tripathi, Shikha, Acien, Alejandro, Holmes, Ashley A, Arroyo-Gallego, Teresa, Giancardo, Luca
DOI: 10.1093/jamia/ocae050