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The application of natural language processing (NLP) in the clinical domain is important due to the rich unstructured information in clinical documents, which often remains inaccessible in structured data. When applying NLP methods to a certain domain, the role of benchmark datasets is crucial as benchmark datasets not only guide the selection of best-performing models but also enable the assessment of the reliability of the generated outputs. Despite the recent [...]

The rapid advancement of artificial intelligence (AI) has led to significant transformations in health and healthcare. As AI technologies continue to evolve, there is an urgent need to establish a unified framework that guides the design, implementation, and evaluation of AI-driven interventions across individual and population health contexts.

Applying large language models (LLMs) to the clinical domain is challenging due to the context-heavy nature of processing medical records. Retrieval-augmented generation (RAG) offers a solution by facilitating reasoning over large text sources. However, there are many parameters to optimize in just the retrieval system alone. This paper presents an ablation study exploring how different embedding models and pooling methods affect information retrieval for the clinical domain.

To pilot a digital health technologies ecosystem known as project SingaporeWALK (Wearables and Apps for Community Living and Knowledge) that build capacity in older adults, senior center managers, health coaches, and caregivers in using health technologies (eg, wearables, apps, exergames) collaboratively in a gamified way for active aging.

In the general hospital wards, machine learning (ML)-based early warning systems (EWSs) can identify patients at risk of deterioration to facilitate rescue interventions. We assess subpopulation performance of a ML-based EWS on medical and surgical adult patients admitted to general hospital wards.

Measurement of health-related social needs (HRSNs) is complex. We sought to develop and validate computable phenotypes (CPs) using structured electronic health record (EHR) data for food insecurity, housing instability, financial insecurity, transportation barriers, and a composite-type measure of these, using human-defined rule-based and machine learning (ML) classifier approaches.

The phenome-wide association study (PheWAS) systematically examines the phenotypic spectrum extracted from electronic health records (EHRs) to uncover correlations between phenotypes and exposures. This review explores methodologies, highlights challenges, and outlines future directions for EHR-driven PheWAS.

To be usable, useful, and sustainable for families of children with medically complex conditions (CMC), digital interventions must account for the complex sociotechnical context in which these families provide care. CMC experience higher neighborhood socioeconomic disadvantage than other child populations, which has associations with CMC health. Neighborhoods may influence the structure and function of the array of caregivers CMC depend upon (ie, the caregiving network).

The automatic detection of stance on social media is an important task for public health applications, especially in the context of health crises. Unfortunately, existing models are typically trained on English corpora. Considering the benefits of extending research to other widely spoken languages, the goal of this study is to develop stance detection models for social media posts in Spanish.