Drug-drug interaction through molecular structure similarity analysis.
Drug-drug interactions (DDIs) are responsible for many serious adverse events; their detection is crucial for patient safety but is very challenging. Currently, the US Food and Drug Administration and pharmaceutical companies are showing great interest in the development of improved tools for identifying DDIs.
Author(s): Vilar, Santiago, Harpaz, Rave, Uriarte, Eugenio, Santana, Lourdes, Rabadan, Raul, Friedman, Carol
DOI: 10.1136/amiajnl-2012-000935