Search AMIA.org

Sharing clinical data for research that is both collaborative and privacy-preserving remains a challenge. Differential privacy (DP) offers a solution by introducing noise to query results. Using the PrivateSQL DP platform, this study assesses the resulting utility of differentially private data at different levels of aggregation through analyses of COVID-19 pandemic associations with new cancer diagnosis counts (NCCs).

Clinician perspectives on machine learning and artificial intelligence (ML/AI) vary with discipline. However, fewer studies describe patient perspectives and address medical situations that require rapid decisions with durable consequences for patient outcomes. This study characterized perspectives (qualitatively) and sentiment (quantitatively) regarding the use of ML/AI for patient management in neurological emergencies.

Critically ill patients are managed with complex medication regimens that require medication management to optimize safety and efficacy. When performed by a critical care pharmacist (CCP), discrete medication management activities are termed medication interventions. The ability to define CCP workflow and intervention timeliness depends on the ability to predict the medication management needs of individual intensive care unit (ICU) patients. The purpose of this study was to develop prediction models [...]

A point-of-care resource is required to support Registered Dietitian Nutritionists (RDNs) in providing comprehensive culturally-tailored nutrition services. This study aims to describe the iterative development and testing of a comprehensive nutrition assessment tool as part of a novel web-based platform to Support Personalized and Inclusive Cuisines in Environments for Healthcare (SPICE-Healthcare).

To address the challenges of data heterogeneity and manual feature engineering in clinical predictive modeling, we introduce FHIR-Former, an open-source framework integrating Fast Healthcare Interoperability Resources (FHIR) with large language models (LLMs) to automate and standardize clinical prediction tasks.

To evaluate the accuracy, computational cost, and portability of a new natural language processing (NLP) method for extracting medication information from clinical narratives.

In medical research and education, generative artificial intelligence/machine learning (AI/ML) models to synthesize artificial medical data can enable the sharing of high-quality data while preserving the privacy of patients. Given that such data is often high-dimensional, a relevant consideration is whether to synthesize the entire dataset when only a task-relevant subset is needed. This study evaluates how the number of variables in training impacts fidelity, utility, and privacy of the [...]

Acute otitis media (AOM) is a leading cause of pediatric antibiotic overuse. Safety Net Antibiotic Prescriptions (SNAPs) are recommended for antibiotic stewardship but are difficult to identify due to lack of structured documentation.

Longitudinal data in electronic health records (EHRs) represent an individual's clinical history through a sequence of codified concepts, including diagnoses, procedures, medications, and laboratory tests. Generative pretrained transformers (GPT) can leverage this data to predict future events. While fine-tuning of these models can enhance task-specific performance, it becomes costly when applied to many clinical prediction tasks. In contrast, a pretrained foundation model can be used in zero-shot forecasting setting, offering [...]

To assess whether HL7 Fast Healthcare Interoperability Resources (FHIR) can underpin a fully standards-based, end-to-end digital research architecture, demonstrate it in a live study, and quantify its benefits for interoperability and development efficiency.