Integrating State-Space Modeling, Parameter Estimation, Deep Learning, and Docking Techniques in Drug Repurposing: A Case Study on COVID-19 Cytokine Storm.
This study addresses the significant challenges posed by emerging SARS-CoV-2 variants, particularly in developing diagnostics and therapeutics. Drug repurposing is investigated by identifying critical regulatory proteins impacted by the virus, providing rapid and effective therapeutic solutions for better disease management.
Author(s): Bakshi, Abhisek, Gangopadhyay, Kaustav, Basak, Sujit, De, Rajat K, Sengupta, Souvik, Dasgupta, Abhijit
DOI: 10.1093/jamia/ocaf035