Using indication embeddings to represent patient health for drug safety studies.
The electronic health record is a rising resource for quantifying medical practice, discovering the adverse effects of drugs, and studying comparative effectiveness. One of the challenges of applying these methods to health care data is the high dimensionality of the health record. Methods to discover the effects of drugs in health data must account for tens of thousands of potentially relevant confounders. Our goal in this work is to reduce [...]
Author(s): Melamed, Rachel D
DOI: 10.1093/jamiaopen/ooaa040