Development and application of pharmacological statin-associated muscle symptoms phenotyping algorithms using structured and unstructured electronic health records data.
Statins are widely prescribed cholesterol-lowering medications in the United States, but their clinical benefits can be diminished by statin-associated muscle symptoms (SAMS), leading to discontinuation.
Author(s): Sun, Boguang, Yew, Pui Ying, Chi, Chih-Lin, Song, Meijia, Loth, Matt, Zhang, Rui, Straka, Robert J
DOI: 10.1093/jamiaopen/ooad087