Harnessing the power of large language models for clinical tasks and synthesis of scientific literature.
Author(s): Bakken, Suzanne
DOI: 10.1093/jamia/ocaf071
Author(s): Bakken, Suzanne
DOI: 10.1093/jamia/ocaf071
This study aims to summarize the usage of large language models (LLMs) in the process of creating a scientific review by looking at the methodological papers that describe the use of LLMs in review automation and the review papers that mention they were made with the support of LLMs.
Author(s): Scherbakov, Dmitry, Hubig, Nina, Jansari, Vinita, Bakumenko, Alexander, Lenert, Leslie A
DOI: 10.1093/jamia/ocaf063
As large language models (LLMs) are integrated into electronic health record (EHR) workflows, validated instruments are essential to evaluate their performance before implementation and as models and documentation practices evolve. Existing instruments for provider documentation quality are often unsuitable for the complexities of LLM-generated text and lack validation on real-world data. The Provider Documentation Summarization Quality Instrument (PDSQI-9) was developed to evaluate LLM-generated clinical summaries. This study aimed to validate [...]
Author(s): Croxford, Emma, Gao, Yanjun, Pellegrino, Nicholas, Wong, Karen, Wills, Graham, First, Elliot, Schnier, Miranda, Burton, Kyle, Ebby, Cris, Gorski, Jillian, Kalscheur, Matthew, Khalil, Samy, Pisani, Marie, Rubeor, Tyler, Stetson, Peter, Liao, Frank, Goswami, Cherodeep, Patterson, Brian, Afshar, Majid
DOI: 10.1093/jamia/ocaf068
Clinical staff often help clinicians review and respond to messages from patients. This study aimed to characterize primary care staff members' experiences with inbox work.
Author(s): Rule, Adam, Vang, Phillip, Micek, Mark A, Arndt, Brian G
DOI: 10.1093/jamia/ocaf067
The primary objective was to compile a comprehensive list of Logical Observation Identifiers Names and Codes (LOINC) terms that may be associated with patient, healthcare provider, and healthcare facility identifying information.
Author(s): Nourelahi, Mehdi, Sadhu, Eugene M, Samayamuthu, Malarkodi J, Visweswaran, Shyam
DOI: 10.1093/jamia/ocaf061
The objective was to understand the association between people with adequate and inadequate health literacy (HL) in the All of Us cohort.
Author(s): O'Leary, Catina, Eder, Milton Mickey, Goli, Sumana, Pettyjohn, Sam, Rattine-Flaherty, Elizabeth, Jatt, Yousra, Cottler, Linda B
DOI: 10.1093/jamia/ocae225
This study aims to develop and evaluate an approach using large language models (LLMs) and a knowledge graph to triage patient messages that need emergency care. The goal is to notify patients when their messages indicate an emergency, guiding them to seek immediate help rather than using the patient portal, to improve patient safety.
Author(s): Liu, Siru, Wright, Aileen P, McCoy, Allison B, Huang, Sean S, Steitz, Bryan, Wright, Adam
DOI: 10.1093/jamia/ocaf059
Author(s): Shyr, Cathy, Harris, Paul A
DOI: 10.1093/jamia/ocaf026
Large language models (LLMs) have shown potential in biomedical applications, leading to efforts to fine-tune them on domain-specific data. However, the effectiveness of this approach remains unclear. This study aims to critically evaluate the performance of biomedically fine-tuned LLMs against their general-purpose counterparts across a range of clinical tasks.
Author(s): Dorfner, Felix J, Dada, Amin, Busch, Felix, Makowski, Marcus R, Han, Tianyu, Truhn, Daniel, Kleesiek, Jens, Sushil, Madhumita, Adams, Lisa C, Bressem, Keno K
DOI: 10.1093/jamia/ocaf045
Diagnosis codes documented in electronic health records (EHR) are often relied upon to clinically phenotype patients for biomedical research. However, these diagnoses can be incomplete and inaccurate, leading to false negatives when searching for patients with phenotypes of interest. This study aims to determine whether PheMAP, a comprehensive knowledgebase integrating multiple clinical terminologies beyond diagnosis to capture phenotypes, can effectively identify patients lacking relevant EHR diagnosis codes.
Author(s): Yan, Chao, Grabowska, Monika E, Thakkar, Rut, Dickson, Alyson L, Embí, Peter J, Feng, QiPing, Denny, Joshua C, Kerchberger, Vern Eric, Malin, Bradley A, Wei, Wei-Qi
DOI: 10.1093/jamia/ocaf055