Adapting machine learning models to temporal drift: oral mucositis prediction in head and neck cancer patients receiving proton and carbon ion therapy.
Temporal drift, defined as changes over time in underlying data distributions, can degrade the performance of clinical prediction models. In head and neck cancer (HNC) radiotherapy, evolving proton and carbon ion therapies may shift the risk of oral mucositis over time. This study aimed to compare machine learning (ML) strategies for mitigating temporal drift in predicting grade ≥2 oral mucositis among patients treated with particle therapy.
Author(s): Wang, Yiqiao, Zhang, Zhihong, Zhu, Yu, Wang, Ziying, Ning, Renli, Zhang, Lijuan, Wan, Hongwei
DOI: 10.1093/jamia/ocag025