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Phase II of MVP-CHAMPION, a federal collaboration between the Veterans Affairs Healthcare System (VA) and the Department of Energy (DoE), leveraged large-scale clinical, geo-spatial, and genetic data with state-of-the-art artificial intelligence (AI), and high-performance computing (HPC) to improve value in healthcare.

Human Factors (HF) methods have potential to ensure the design of health information technology (HIT) is safe and usable, but limited research has examined what HF methods have been applied or could be applied to HIT. This study aimed to identify key HF and safety analysis methods used and/or recommended by HF experts working in healthcare or non-healthcare industries that may be suitable for supporting the design, redesign and configuration [...]

To propose an equity-by-design agenda for socially assistive robots (SARs) as embodied digital health informatics interventions.

Secondary headaches require urgent recognition due to potentially devastating consequences if untreated. Despite established clinical "red flag" criteria, identifying patients needing immediate evaluation remains challenging in primary care. This study developed and evaluated a large language model (LLM)-based multi-agent clinical decision support system for interpretable secondary headache diagnosis.

Clinical named entity recognition tools commonly map free text to Unified Medical Language System (UMLS) Concept Unique Identifiers (CUIs). For many downstream tasks, however, the clinically meaningful unit is not a single CUI but a concept set comprising related synonyms, subtypes, and associated concepts. Constructing these sets is labour-intensive, inconsistently performed, and poorly supported by existing tools.

Clinical decision support (CDS) is increasingly delivered through distributed architectures that connect electronic health record (EHR) workflows to external services and community partners. While these designs enable rapid deployment and interoperability, they also introduce new failure modes that can silently disrupt time‑sensitive care processes. Practical, real‑world descriptions of these distributed CDS malfunctions remain limited.

Using AI algorithms can exacerbate health disparities if care or resources are allocated away from underserved populations. We evaluated an algorithm for its potential to worsen health disparities across different clinical use cases.

Missed healthcare appointments, or "Did Not Attends" (DNAs), pose challenges for healthcare systems. Technology-facilitated reminder systems, such as SMS and phone calls are often implemented to improve attendance. This scoping review aimed to map the evidence on patient and carer perspectives and experiences of technology-enabled appointment reminders in healthcare and, secondly, examine how equity-relevant characteristics were reported.

The 2025 American College of Medical Informatics (ACMI) Symposium, themed Charting the Future of ACMI, provided a forum for fellows to reflect on the 2020-2025 ACMI Strategic Plan and define future priorities. Discussions centered on: (1) mobilizing ACMI's expertise to guide the responsible use of artificial intelligence (AI) in medical informatics, (2) advancing informatics education and mentorship across career stages, and (3) strengthening local, national, and global interdisciplinary partnerships. Proposed [...]

This study compares the contents of two data standards; the Observational Medical Outcomes Partnership (OMOP) and Fast Healthcare Interoperability Resources (FHIR), highlighting their strength and weaknesses and serve as an initial step toward understanding how each standard supports secondary data analysis.