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Appropriate Use Criteria Clinical Decision Support (AUC CDS) was legislatively mandated in the United States in 2014, and multiple CDS vendors were designated as qualified Clinical Decision Support Mechanisms by the Centers for Medicare and Medicaid Services. Little is known about the costs and benefits of these systems in real-world settings.

Interruptive clinical decision support (CDS) alerts are intended to improve patient care but can contribute to alert fatigue, diminishing their effectiveness. The alert demonstrated minimal clinical effect while contributing significantly to alert fatigue.

Despite its morbidity, mortality, and financial burden, in-hospital malnutrition remains underdiagnosed and undertreated. Artificial intelligence offers a promising clinical informatics solution for identifying malnutrition risk and one that can be coupled with clinician-delivered patient care.

In 2023, AMIA's Inclusive Language and Context Style Guidelines (the "Guidelines") were approved by the Board of Directors and made a publicly available resource. This work began in 2021 through AMIA's DEI Task Force and subsequent DEI Committee; many members provided input, feedback, and time to create the Guidelines. In this paper, the authors provide a transparent account of the origin, development, contents, and dissemination of the Guidelines and share [...]

Fairness concerns stemming from known and unknown biases in healthcare practices have raised questions about the trustworthiness of Artificial Intelligence (AI)-driven Clinical Decision Support Systems (CDSS). Studies have shown unforeseen performance disparities in subpopulations when applied to clinical settings different from training. Existing unfairness mitigation strategies often struggle with scalability and accessibility, while their pursuit of group-level prediction performance parity does not effectively translate into fairness at the point of [...]

Background Children with a difficult airway are at high risk of decompensation in the setting of respiratory distress. Situational awareness among all team members, and a shared plan in case of an emergency, can reduce the chance of catastrophic outcomes. Methods We developed clinical decision support (CDS) to improve difficult airway situational awareness while minimizing alert burden. Three iterative designs were developed and implemented from 2015 through 2023. We measured [...]

This study aims to tackle the critical challenge of adapting deep learning (DL) models for deployment in real-world healthcare settings, specifically focusing on catastrophic forgetting due to distribution shifts between hospital and non-hospital environments. Metabolic syndrome (MetS) is susceptible to misdiagnosis by DL models due to distribution shifts. This work demonstrates the potential of continual learning (CL) to enhance model performance in MetS identification across diverse settings.

Extracting social determinants of health (SDoHs) from medical notes depends heavily on labor-intensive annotations, which are typically task-specific, hampering reusability and limiting sharing. Here, we introduce SDoH-GPT, a novel framework leveraging few-shot learning large language models (LLMs) to automate the extraction of SDoH from unstructured text, aiming to improve both efficiency and generalizability.

The CONCERN Early Warning System (CONCERN EWS) is an artificial intelligence based clinical decision support system (AI-CDSS) for prediction of clinical deterioration leveraging signals from nursing documentation patterns. While a recent multi-site randomized controlled trial demonstrated its effectiveness in reducing inpatient mortality and length of stay, evaluating implementation outcomes is essential to ensure equitable results across patient populations.