Parameterizing time in electronic health record studies.
Fields like nonlinear physics offer methods for analyzing time series, but many methods require that the time series be stationary-no change in properties over time.Objective Medicine is far from stationary, but the challenge may be able to be ameliorated by reparameterizing time because clinicians tend to measure patients more frequently when they are ill and are more likely to vary.
Author(s): Hripcsak, George, Albers, David J, Perotte, Adler
DOI: 10.1093/jamia/ocu051