A system to build distributed multivariate models and manage disparate data sharing policies: implementation in the scalable national network for effectiveness research.
Centralized and federated models for sharing data in research networks currently exist. To build multivariate data analysis for centralized networks, transfer of patient-level data to a central computation resource is necessary. The authors implemented distributed multivariate models for federated networks in which patient-level data is kept at each site and data exchange policies are managed in a study-centric manner.
Author(s): Meeker, Daniella, Jiang, Xiaoqian, Matheny, Michael E, Farcas, Claudiu, D'Arcy, Michel, Pearlman, Laura, Nookala, Lavanya, Day, Michele E, Kim, Katherine K, Kim, Hyeoneui, Boxwala, Aziz, El-Kareh, Robert, Kuo, Grace M, Resnic, Frederic S, Kesselman, Carl, Ohno-Machado, Lucila
DOI: 10.1093/jamia/ocv017