Large language models in biomedicine and health: current research landscape and future directions.
Author(s): Lu, Zhiyong, Peng, Yifan, Cohen, Trevor, Ghassemi, Marzyeh, Weng, Chunhua, Tian, Shubo
DOI: 10.1093/jamia/ocae202
Author(s): Lu, Zhiyong, Peng, Yifan, Cohen, Trevor, Ghassemi, Marzyeh, Weng, Chunhua, Tian, Shubo
DOI: 10.1093/jamia/ocae202
This paper aims to address the challenges in abstract screening within systematic reviews (SR) by leveraging the zero-shot capabilities of large language models (LLMs).
Author(s): Akinseloyin, Opeoluwa, Jiang, Xiaorui, Palade, Vasile
DOI: 10.1093/jamia/ocae166
The recent surge in large language models (LLMs) across various fields has yet to be fully realized in traditional Chinese medicine (TCM). This study aims to bridge this gap by developing a large language model tailored to TCM knowledge, enhancing its performance and accuracy in clinical reasoning tasks such as diagnosis, treatment, and prescription recommendations.
Author(s): Hua, Rui, Dong, Xin, Wei, Yu, Shu, Zixin, Yang, Pengcheng, Hu, Yunhui, Zhou, Shuiping, Sun, He, Yan, Kaijing, Yan, Xijun, Chang, Kai, Li, Xiaodong, Bai, Yuning, Zhang, Runshun, Wang, Wenjia, Zhou, Xuezhong
DOI: 10.1093/jamia/ocae087
This study aims to evaluate the utility of large language models (LLMs) in healthcare, focusing on their applications in enhancing patient care through improved diagnostic, decision-making processes, and as ancillary tools for healthcare professionals.
Author(s): Zhang, Jingqing, Sun, Kai, Jagadeesh, Akshay, Falakaflaki, Parastoo, Kayayan, Elena, Tao, Guanyu, Haghighat Ghahfarokhi, Mahta, Gupta, Deepa, Gupta, Ashok, Gupta, Vibhor, Guo, Yike
DOI: 10.1093/jamia/ocae184
To investigate approaches of reasoning with large language models (LLMs) and to propose a new prompting approach, ensemble reasoning, to improve medical question answering performance with refined reasoning and reduced inconsistency.
Author(s): Lucas, Mary M, Yang, Justin, Pomeroy, Jon K, Yang, Christopher C
DOI: 10.1093/jamia/ocae131
To examine whether comfort with the use of ChatGPT in society differs from comfort with other uses of AI in society and to identify whether this comfort and other patient characteristics such as trust, privacy concerns, respect, and tech-savviness are associated with expected benefit of the use of ChatGPT for improving health.
Author(s): Platt, Jodyn, Nong, Paige, Smiddy, Renée, Hamasha, Reema, Carmona Clavijo, Gloria, Richardson, Joshua, Kardia, Sharon L R
DOI: 10.1093/jamia/ocae164
Large language models (LLMs) have demonstrated remarkable generalization and across diverse tasks, leading individuals to increasingly use them as personal assistants due to their emerging reasoning capabilities. Nevertheless, a notable obstacle emerges when including numerical/temporal data into these prompts, such as data sourced from wearables or electronic health records. LLMs employ tokenizers in their input that break down text into smaller units. However, tokenizers are not designed to represent numerical [...]
Author(s): Spathis, Dimitris, Kawsar, Fahim
DOI: 10.1093/jamia/ocae090
To assess the performance of large language models (LLMs) for zero-shot disambiguation of acronyms in clinical narratives.
Author(s): Kugic, Amila, Schulz, Stefan, Kreuzthaler, Markus
DOI: 10.1093/jamia/ocae157
To investigate the demonstration in large language models (LLMs) for biomedical relation extraction. This study introduces a framework comprising three types of adaptive tuning methods to assess their impacts and effectiveness.
Author(s): Zhou, Huixue, Li, Mingchen, Xiao, Yongkang, Yang, Han, Zhang, Rui
DOI: 10.1093/jamia/ocae147
Investigate the use of advanced natural language processing models to streamline the time-consuming process of writing and revising scholarly manuscripts.
Author(s): Pividori, Milton, Greene, Casey S
DOI: 10.1093/jamia/ocae139