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Primary graft dysfunction (PGD) is an essential outcome after the heart transplant, which causes severe complications and symptoms for recipients. The in advance prediction of PGD can help the transplant physician better manage the risks of PGD occurrence for patients. Domain experts have identified some important risk factors leading to PGD. However, a widely accepted PGD prediction method is lacking from a computational perspective. In this work, we focus on [...]

Automated data extraction from echocardiography reports could facilitate large-scale registry creation and clinical surveillance of valvular heart diseases (VHD). We evaluated the performance of open-source large language models (LLMs) guided by prompt instructions and chain of thought (CoT) for this task.

Establishing a robust and secure framework allowing creation and sharing of custom features within the REDCap electronic data capture platform.

Screening Brief Intervention and Referral to Treatment (SBIRT) can reduce the health and social costs associated with unhealthy alcohol use (UAU). Electronic health records (EHRs) can support evidence-based screening practices for UAU and provide performance data needed for quality improvement. The objective of this study was to describe barriers faced by primary care clinics when using EHR systems to support UAU screening and delivery of recommended interventions.

Despite the benefits of Clinical Decision Support (CDS), concerns of potential risks arise amidst increasing reports of CDS malfunctions. Without objective and standard methods to evaluate CDS in post-live stage, CDS performance in dynamic healthcare environment remains a black box from user perspective. In this study, we proposed a comprehensive framework to identify and evaluate post-live CDS malfunctions from the perspective of healthcare settings.

Family data are a valuable data source in bioinformatic research. This is because family members often share common genetic and environmental exposures. Collecting this family data is traditionally very labor intensive but advances in electronic health record (EHR) data mining has proven useful when identifying pedigrees linked to longitudinal health histories. These are called e-pedigrees. Unfortunately, e-pedigrees tend to miss the oldest patients who inherently have the longest and richest [...]

The integration of predictive models into live clinical care requires scientific testing before implementation to ensure patient safety. We built and technically implemented a model that predicts which patients require an electrocardiogram (ECG) to screen for heart attacks within 10 minutes of their arrival to the Emergency Department. We developed a structured framework for the in vitro to in vivo translation of the model through implementation as clinical decision support [...]

Clinicians retrieve data from electronic health record (EHR) systems and summarize them into clinical information to accomplish clinical reasoning and decision-making tasks. Visualization, using meaningful summarization methods and intuitive presentation approaches, can enhance this process. This systematic review examines how EHR data are summarized, visualized, and aligned with the 7 clinical reasoning and decision-making tasks shared by clinicians.

Telemedicine use has surged since the COVID-19 pandemic, offering a convenient way for patients to access healthcare. Whereas digital literacy (general comfort with and ability to use digital tools) is necessary to utilize telemedicine, digital health literacy is a subset of this, focusing on the ability to use digital tools to seek out, understand, and utilize health information. As such, barriers such as the lack of high-speed internet and limited [...]

Electronic health records (EHRs) provide substantial resources for observational studies, yet present significant challenges in safeguarding patient privacy while maintaining research quality. Differential privacy (DP) offers a quantifiable privacy guarantee; however, its impact on observational studies remains underexplored. We empirically evaluated the effects of DP across varying values of its privacy parameter, epsilon, on case-control analysis outcomes using EHR data. This study aims to inform DP parameter selection and examines [...]