Reformulating patient stratification for targeting interventions by accounting for severity of downstream outcomes resulting from disease onset: a case study in sepsis.
To quantify differences between (1) stratifying patients by predicted disease onset risk alone and (2) stratifying by predicted disease onset risk and severity of downstream outcomes. We perform a case study of predicting sepsis.
Author(s): Kamran, Fahad, Tjandra, Donna, Valley, Thomas S, Prescott, Hallie C, Shah, Nigam H, Liu, Vincent X, Horvitz, Eric, Wiens, Jenna
DOI: 10.1093/jamia/ocaf036